发明公开
EP1491537A1 HYDROXYMORPHOLINONE DERIVATIVE AND MEDICINAL USE THEREOF
有权
羟基磷酸二甲酯在DESSEN MEDIZINISCHE VERWENDUNG
- 专利标题： HYDROXYMORPHOLINONE DERIVATIVE AND MEDICINAL USE THEREOF
- 专利标题（中）： 羟基磷酸二甲酯在DESSEN MEDIZINISCHE VERWENDUNG
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申请号： EP03745432.9申请日： 2003-03-27
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公开(公告)号： EP1491537A1公开(公告)日： 2004-12-29
- 发明人: NAKAMURA, Masayuki , INOUE, Jun
- 申请人： Senju Pharmaceutical Co., Ltd.
- 申请人地址： 5-8, Hiranomachi 2-chome, Chuo-Ku Osaka-shi, Osaka 541-0046 JP
- 专利权人： Senju Pharmaceutical Co., Ltd.
- 当前专利权人： Senju Pharmaceutical Co., Ltd.
- 当前专利权人地址： 5-8, Hiranomachi 2-chome, Chuo-Ku Osaka-shi, Osaka 541-0046 JP
- 代理机构： von Kreisler, Alek, Dipl.-Chem.
- 优先权： JP2002097176 20020329
- 国际公布： WO2003082837 20031009
- 主分类号： C07D265/32
- IPC分类号： C07D265/32 ; A61K31/5375 ; A61P9/00 ; A61P9/10 ; A61P19/10 ; A61P25/00 ; A61P25/28 ; A61P27/02 ; A61P27/06 ; A61P27/12 ; A61P37/02 ; A61P43/00
摘要：
A compound represented by the following formula (I)
wherein R 1 and R 2 are each a lower alkyl group optionally having substituents, which has a calpain inhibitory activity, or a salt thereof is provided.
wherein R 1 and R 2 are each a lower alkyl group optionally having substituents, which has a calpain inhibitory activity, or a salt thereof is provided.
公开/授权文献
- EP1491537B1 HYDROXYMORPHOLINONE DERIVATIVE AND MEDICINAL USE THEREOF 公开/授权日：2010-07-07
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