发明公开
- 专利标题： NOVEL PROTEINS AND NUCLEIC ACIDS ENCODING SAME
- 专利标题（中）： 新的蛋白质和核酸FOR THIS ENCODE
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申请号： EP02806720.5申请日： 2002-08-02
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公开(公告)号： EP1492807A2公开(公告)日： 2005-01-05
- 发明人: ZERHUSEN, Bryan, D , PATTURAJAN, Meera , KEKUDA, Ramesh , MILLER, Charles, E , RIEGER, Daniel,K , PENA, Carol,E, A , SHIMKETS, Richard, A , LI,Li , BERGHS, Constance , ZHONG, Mei , CASMAN, Stacie, J , VOSS, Edward, Z , BOLDOG,Ferenc, L , PADIGARU, Muralidhara , SMITHSON, Glennda , SHENOY, Suresh, G , JI, Weizhen , GORMAN, Linda , VERNET, Corine, A, M. , LEITE, Mario, W , GUO, Xiaojia , ANDERSON, David, W , SPYTEK, Kimberly,A , GERLACH, Valerie, L , BURGESS, Catherine, E , KHRAMTSOV, Nikolai, V , ORT, Tatiana , ELLERMAN, Karen , RASTELLI, Luca , AGEE, Michele, L , CHAUDHURI, Amitabha , CHANT, John, S , DIPIPPO, Vicent, A , EDINGER, Shlomit, R , EISEN, Andrew , GANGOLLI, Esha,A , GIOT, Loic , OOI, Chean, Eng , ROTHENBERG, Mark, E , SPADERNA, Steven,K , HJALT, Tord , LIU, Xiaohong , TAUPIER, Raymond J,Jr , CATTERTON, Elina
- 申请人： Curagen Corporation
- 申请人地址： 11th floor, 555 Long Wharf Drive New Haven, CT 06511 US
- 专利权人： Curagen Corporation
- 当前专利权人： Curagen Corporation
- 当前专利权人地址： 11th floor, 555 Long Wharf Drive New Haven, CT 06511 US
- 代理机构： MacLean, Martin Robert
- 优先权： US309501P 20010802; US310291P 20010803; US310951P 20010808; US311292P 20010809; US311979P 20010813; US312203P 20010814; US313156P 20010817; US313201P 20010817; US313702P 20010820; US314031P 20010821; US314466P 20010823; US315403P 20010828; US315853P 20010829; US316508P 20010831; US323936P 20010921; US338078P 20011203; US354655P 20020205; US361764P 20020305; US373825P 20020419; US380980P 20020515; US380971P 20020515; US381039P 20020516; US383761P 20020528; US383887P 20020529; US210130 20020801
- 国际公布： WO2003076642 20030918
- 主分类号： C07H21/04
- IPC分类号： C07H21/04
摘要：
The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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