发明公开
EP1497307A2 RECOMBINANT P.FALCIPARUM MEROZOITE PROTEIN-1 42 VACCINE
有权
疫苗与重组腺病毒恶性疟原虫MEROZOITPROTEIN-1 42
- 专利标题： RECOMBINANT P.FALCIPARUM MEROZOITE PROTEIN-1 42 VACCINE
- 专利标题（中）： 疫苗与重组腺病毒恶性疟原虫MEROZOITPROTEIN-1 42
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申请号： EP03726193.0申请日： 2003-04-01
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公开(公告)号： EP1497307A2公开(公告)日： 2005-01-19
- 发明人: ANGOV, Evelina , LYON, Jeffery, A. , DARKO, Christian, Asare , COHEN, Joe, D.
- 申请人： Walter Reed Army Institute of Research
- 申请人地址： Department of the Army,Walter Reed Army Medical Center Washington, DC 20307-5100 US
- 专利权人： Walter Reed Army Institute of Research
- 当前专利权人： Walter Reed Army Institute of Research
- 当前专利权人地址： Department of the Army,Walter Reed Army Medical Center Washington, DC 20307-5100 US
- 代理机构： Sexton, Jane Helen
- 优先权： US369741P 20020401; US379688P 20020509
- 国际公布： WO2003084472 20031016
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C07H21/02 ; C12P21/06 ; C12P21/04 ; C12N15/00
摘要：
In this application is described the expression and purification of a recombinant Plasmodium falciparum (FVO) MSP-1 42 . The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native molecule. The recombinant MSP-1 42 is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.
公开/授权文献
- EP1497307B1 RECOMBINANT P.FALCIPARUM MEROZOITE PROTEIN-1 42 VACCINE 公开/授权日：2016-08-03
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