专利检索 ap:("Walter Reed Army Institute of Research") AND inv:"LYON, Jeffery, A." 第 1 页

1.

发明公开
RECOMBINANT P.FALCIPARUM MEROZOITE PROTEIN-1 42 VACCINE 有权
标题翻译：疫苗与重组腺病毒恶性疟原虫MEROZOITPROTEIN-1 42

公开(公告)号：EP1497307A2

公开(公告)日：2005-01-19

申请号：EP03726193.0

申请日：2003-04-01

申请人： Walter Reed Army Institute of Research

发明人： ANGOV, Evelina , LYON, Jeffery, A. , DARKO, Christian, Asare , COHEN, Joe, D.

IPC分类号： C07H21/04 , C07H21/02 , C12P21/06 , C12P21/04 , C12N15/00

CPC分类号： G01N33/56905 , A61K39/00 , A61K39/015 , C07K14/445 , C07K16/205 , C12N15/67 , C12P21/02 , G01N2333/445 , G01N2800/52 , Y02A50/412

摘要： In this application is described the expression and purification of a recombinant Plasmodium falciparum (FVO) MSP-1 42 . The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native molecule. The recombinant MSP-1 42 is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.

2.

发明授权
RECOMBINANT P.FALCIPARUM MEROZOITE PROTEIN-1 42 VACCINE 有权
标题翻译：疫苗与重组腺病毒恶性疟原虫MEROZOITPROTEIN-1 42

公开(公告)号：EP1497307B1

公开(公告)日：2016-08-03

申请号：EP03726193.0

申请日：2003-04-01

申请人： Walter Reed Army Institute of Research

发明人： ANGOV, Evelina , LYON, Jeffery, A. , DARKO, Christian, Asare , COHEN, Joe, D.

IPC分类号： C07H21/04 , C07H21/02 , C12P21/06 , C12P21/04 , C12N15/00

CPC分类号： G01N33/56905 , A61K39/00 , A61K39/015 , C07K14/445 , C07K16/205 , C12N15/67 , C12P21/02 , G01N2333/445 , G01N2800/52 , Y02A50/412

摘要： In this application is described the expression and purification of a recombinant Plasmodium falciparum (FVO) MSP-1 42 . The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native molecule. The recombinant MSP-1 42 is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.