发明公开
- 专利标题： POLYPEPTIDE BIOMARKERS FOR DIAGNOSING ALZHEIMER'S DISEASE
- 专利标题（中）： 多肽生物标志物诊断阿尔茨海默病
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申请号： EP03792291.1申请日： 2003-08-11
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公开(公告)号： EP1535076A2公开(公告)日： 2005-06-01
- 发明人: YALKINOGLU, Özkan , KÖNIG, Gerhard , HOCHSTRASSER, Denis, Francois , SANCHEZ, Jean-Charles , CARRETTE, Odile
- 申请人： Bayer HealthCare AG
- 申请人地址： 51368 Leverkusen DE
- 专利权人： Bayer HealthCare AG
- 当前专利权人： Bayer HealthCare AG
- 当前专利权人地址： 51368 Leverkusen DE
- 优先权： EP02018283 20020823; EP02026643 20021129
- 国际公布： WO2004019043 20040304
- 主分类号： G01N33/68
- IPC分类号： G01N33/68
摘要：
A method for assessing the state of Alzheimer's disease in patients is disclosed. A method for monitoring the progression of Alzheimer's disease in patients is also disclosed. The method applies detection of specific markers in body fluids (e.g. CSF), using mass spectrometric analysis (SELDI-TOF MS). The specific markers are: human cystatin C, human beta-2-microglobulin, human myoglobin neurosecretory protein VGF or fragments of these proteins.
公开/授权文献
- EP1535076B1 POLYPEPTIDE BIOMARKERS FOR DIAGNOSING ALZHEIMER'S DISEASE 公开/授权日：2008-08-06
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