发明公开
EP1541684A1 SMG-1-BINDING PROTEIN AND METHOD OF SCREENING SUBSTANCE CONTROLLING ITS ACTIVITY
审中-公开
SMG-1结合蛋白和一种筛选及其活动性受监控物质
- 专利标题： SMG-1-BINDING PROTEIN AND METHOD OF SCREENING SUBSTANCE CONTROLLING ITS ACTIVITY
- 专利标题（中）： SMG-1结合蛋白和一种筛选及其活动性受监控物质
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申请号： EP03794253.9申请日： 2003-09-05
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公开(公告)号： EP1541684A1公开(公告)日： 2005-06-15
- 发明人: OHNO, Shigeo , OHNISHI, Tetsuo , YAMASHITA, Akio
- 申请人： Japan Science and Technology Agency , City of Yokohama
- 申请人地址： 1-8, Honcho 4-chome Kawaguchi-shi, Saitama 332-0012 JP
- 专利权人： Japan Science and Technology Agency,City of Yokohama
- 当前专利权人： Japan Science and Technology Agency,City of Yokohama
- 当前专利权人地址： 1-8, Honcho 4-chome Kawaguchi-shi, Saitama 332-0012 JP
- 代理机构： Minderop, Ralph H., Dr. rer. nat.
- 优先权： JP2002260243 20020905
- 国际公布： WO2004022752 20040318
- 主分类号： C12N15/12
- IPC分类号： C12N15/12 ; C12N1/21 ; C12N5/10
摘要：
A novel polypeptide binding to SMG-1, a polynucleotide encoding the same, and a system for screening a substance which artificially modifies an mRNA surveillance mechanism, are disclosed. The polypeptide has an activity of binding to SMG-1, an activity of being phosphorylated by SMG-1, and an activity of modifying SMG-1 activities through these activities.
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