公开(公告)号：EP4534656A1

公开(公告)日：2025-04-09

申请号：EP23816176.4

申请日：2023-05-29

Applicant: Japan Science and Technology Agency

Inventor： MIURA, Fumihito

IPC: C12N5/10 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N15/54 ,  C12N15/63 ,  C12Q1/48 ,  C12Q1/68 ,  C12N9/10

Abstract: The present invention provides a DNA methyltransferase that is capable of recognizing and methylating a short context other than but equivalent to a CG dinucleotide sequence where endogenous methylation occurs, etc. The present invention relates to a protein modified to delete some amino acid residues including the N-terminal end of DNA methyltransferase M.CviQIX or M.CviPII and thereby acquire the ability to specifically recognize a CC dinucleotide sequence and 5-methylate the 5'-position cytosine residue in the sequence, etc.

公开(公告)号：EP4516801A1

公开(公告)日：2025-03-05

申请号：EP23796509.0

申请日：2023-04-27

Applicant: Japan Science and Technology Agency

Inventor： MURAOKA Takahiro ,  UCHIDA Noriyuki ,  FU Jakuei ,  HIGUCHI Genki

IPC: C07K2/00

Abstract: Provided is a compound that includes a peptide structure represented by Formula (p1) or (p2). Also provided is a method for producing droplets using the compound. Xa is an amino acid residue having a hydrophilic side chain; Xb is an amino acid residue having a side chain represented by Formula (b1); Xc and Xd are each independently an amino acid residue or a glycine residue having a hydrophobic side chain; and n is an integer of 1 to 3. Ar 1 is an aryl group or heteroaryl group which may have a substituent; and Ar 2 is an arylene group or a heteroarylene group which may have a substituent.

        XaXb(XaXc) n XaXdXa...     (p1)

        XaXd(XaXc) n XaXbXa...     (p2)

        * -Ar 2 -N=N-Ar 1      (b1)

公开(公告)号：EP4403514A1

公开(公告)日：2024-07-24

申请号：EP22867479.2

申请日：2022-09-12

Applicant: Japan Science and Technology Agency

Inventor： MAJIMA, Yutaka ,  YAMAURA, Junichi ,  KAWACHI, Shiro ,  HOSONO, Hideo ,  TOYAMA, Ryo

IPC: B82B1/00

CPC classification number: B82B1/00

Abstract: To provide a suitable method of producing an ordered-alloy ferromagnetic nanowire structure. Disclosed is a method of producing an ordered-alloy ferromagnetic nanowire structure, the method including: forming a nanowire on or above a substrate, the nanowire having a width of 100 nm or less and a length of at least twice the width, and made of an iron group element and a platinum group element; and subjecting the nanowire to heat treatment to obtain an ordered-alloy ferromagnetic nanowire structure in which an ordered-alloy ferromagnetic nanowire made of an ordered alloy of the iron group element and the platinum group element is formed on or above the substrate.

公开(公告)号：EP4332842A1

公开(公告)日：2024-03-06

申请号：EP22795241.3

申请日：2022-02-18

Applicant: Japan Science and Technology Agency

Inventor： NAKAMURA Yasunobu ,  TABUCHI Yutaka ,  TAMATE Shuhei

IPC: G06N10/40 ,  G06N10/70

Abstract: A quantum computation controller according to one embodiment of the present disclosure has a control signal generator, an observation unit that receives an observation signal indicating the state of each qubit, and a qubit module. The qubit module has a qubit substrate on which a plurality of qubits are arranged, a control circuit, an observation circuit, and a signal processing circuit. The plurality of qubits are grouped into a plurality of groups consisting of a plurality of qubits having the same positional relationship between each qubit and are arranged on the qubit substrate. The control signal generator generates a control signal for performing one or more types of spatially uniform first operation which is an operation for a qubit on the qubit substrate and for performing one or more types of spatially non-uniform second operation, which is an operation for a qubit on the qubit substrate, performed less frequently than the first operation and an instruction signal for causing the control circuit to perform control of the first and the second operations. The control circuit splits the control signal into groups and controls the sending of the control signal to each qubit on the qubit substrate according to the instruction signal. The observation circuit observes the state of each qubit on which the first operation or the second operation has been performed. The signal processing circuit sends the observation signal of each qubit to the observation circuit.

公开(公告)号：EP4250901A2

公开(公告)日：2023-09-27

申请号：EP23185781.4

申请日：2019-10-31

Applicant: Japan Science and Technology Agency

Inventor： NAKAMURA, Yasunobu ,  TABUCHI, Yutaka ,  TAMATE, Shuhei

IPC: H10N69/00

Abstract: A superconducting complex quantum computing circuit includes a circuit substrate in which a wiring pattern of a circuit element, which includes a quantum bit and an observation electrode for observing a state of the quantum bit, and a ground pattern which is at a ground potential are formed on a substrate surface, and that includes a through-electrode which connects the ground pattern formed on a first surface of the substrate surface and the ground pattern formed on a second surface, which is a surface opposite the first surface, inside the substrate; a first ground electrode that includes a first contact portion which is in contact with the ground pattern formed on the first surface of the circuit substrate, and a first non-contact portion which has a shape corresponding to a shape of the wiring pattern formed on the first surface; a second ground electrode that includes a second contact portion which is in contact with the ground pattern formed on the second surface of the circuit substrate; a control signal line that is provided with a contact spring pin at a tip, the pin being in contact with a position corresponding to the quantum bit to press the first surface of the circuit substrate against the first ground electrode or to press the second surface of the circuit substrate against the second ground electrode; and a pressing member that presses the first ground electrode against the first surface of the circuit substrate or presses the second ground electrode against the second surface of the circuit substrate, in which the first ground electrode is in contact with the ground pattern via a first extension portion formed by a superconductor having extensibility higher than extensibility of the ground pattern, and the second ground electrode is in contact with the ground pattern via a second extension portion formed by a superconductor having extensibility higher than the extensibility of the ground pattern.

公开(公告)号：EP3979499A1

公开(公告)日：2022-04-06

申请号：EP20812785.2

申请日：2020-03-18

Applicant: Japan Science and Technology Agency

Inventor： SUGAHARA, Satoshi ,  KITAGATA, Daiki ,  YAMAMOTO, Shuichiro

IPC: H03K3/356 ,  G11C14/00 ,  G11C11/412 ,  G11C11/417

Abstract: Provided is an electronic circuit including a cell array including memory cells each including a bistable circuit that includes a first inverter circuit and a second inverter circuit, each of the first inverter circuit and the second inverter circuit having a first mode characterized by there being substantially no hysteresis in transfer characteristics and a second mode characterized by there being hysteresis in transfer characteristics, wherein each of the first inverter circuit and the second inverter circuit are configured to be switchable between the first mode and the second mode, an output node and an input node of the first inverter circuit being coupled to an input node and an output node of the second inverter circuit, respectively, and a control circuit configured to, after powering off one or more first memory cells that are not required to retain data among the memory cells, put the bistable circuits in remaining one or more second memory cells of the memory cells into the second mode, and supply a second power supply voltage, at which the bistable circuit in the second mode can retain data, to the bistable circuits in the one or more second memory cells while maintaining the second mode, the second power supply voltage being lower than a first power supply voltage that is supplied to the bistable circuit when data is read and/or written.

公开(公告)号：EP3932546A1

公开(公告)日：2022-01-05

申请号：EP20762193.9

申请日：2020-02-26

Applicant: Japan Science and Technology Agency

Inventor： KITANO, Masaaki ,  HOSONO, Hideo ,  YOKOYAMA, Toshiharu ,  KUJIRAI, Jun

IPC: B01J27/24 ,  B01J32/00 ,  B01J37/08 ,  C01B21/092 ,  C01C1/02

Abstract: The invention provides a perovskite-type oxynitride hydride which can be easily synthesized by achieving both improvement in catalytic performance and stabilization when used as a support of a catalyst. The oxynitride hydride is represented by general formula (1a) or (1b).

        ABO 3-x N y H z      (1a)

        AB 2 O 4-x N y H z      (lb)


(In the above general formulas (1 a) and (1 b), A is at least one selected from the group consisting of Ba and Sr; B is at least one selected from the group consisting of Ce, La and Y; x represents a number represented by 0.2 ≤ x ≤ 2.0; y represents a number represented by 0.1 ≤ y ≤ 1.0; and z represents a number represented by 0.1 ≤ z ≤ 1.0.)

公开(公告)号：EP3763714A1

公开(公告)日：2021-01-13

申请号：EP19763778.8

申请日：2019-03-04

Applicant: Japan Science and Technology Agency

Inventor： SAITO Shohei ,  YABU Hiroshi ,  ABE Hiroya

IPC: C07D487/04 ,  C07D471/06 ,  C08G18/38 ,  C07D313/14 ,  C07D405/14 ,  C07D487/22

Abstract: Provided is a compound having higher fluorescence quantum yield and higher optical stability than a conventional FLAP and a polymer compound containing the compound.
The object is achieved by providing a compound represented by the following general Formula (1).

Symbols in general Formula (1) are defined as follows:
A denotes a seven-membered ring or eight-membered ring structure,
Y 1 and Y 2 each denote, independently, a halogen atom or the like,
a1 denotes the number of the substituent groups Y 1 , and a2 denotes the number of the substituent groups Y 2 ,
Y 3 denotes a halogen atom or the like,
b denotes the number of the substituent groups Y 3 ,
m and n each denote, independently, an integer greater than or equal to 0 and less than or equal to 3, when m is an integer greater than or equal to 1 and less than or equal to 3, Y 1 may be substituted with a structure portion defined by m, and similarly, when n is an integer greater than or equal to 1 and less than or equal to 3, Y 2 may be substituted with a structure portion defined by n, and
B 1 and B 2 each denote, independently, any of the structures represented by the following general Formulas (2-1) to (2-3).

Symbols in general Formulas (2-1) to (2-3) are defined as follows:
C 1 denotes a structure containing a cyclic hydrocarbon compound,
C 2 and C 3 each denote a structure containing a cyclic hydrocarbon compound,
D 1 , D 2 , and D 3 each denote a substructure that inhibits aggregation,
E 1 , E 2 , and E 3 each denote a polymerizable substructure,
Z 1 each denote, independently, a hydrogen atom or the like,
c denotes the number of substituent groups Z 1 , and
Z 2 and Z 3 each denote, independently a hydrogen atom or the like, and Z 2 and Z 3 may each form a ring with C 2 , independently.

公开(公告)号：EP3278342B1

公开(公告)日：2020-11-25

申请号：EP16774346.7

申请日：2016-04-01

Applicant: The Florida State University Research Foundation, Incorporated ,  Japan Science and Technology Agency

Inventor： WEISS, Jeremy ,  YAMAMOTO, Akiyasu ,  HELLSTROM, Eric

IPC: H01F6/00 ,  H01L39/12

公开(公告)号：EP3708650A1

公开(公告)日：2020-09-16

申请号：EP20167102.1

申请日：2015-09-18

Applicant: Japan Science and Technology Agency

Inventor： KAWAOKA, Yoshihiro ,  WATANABE, Tokiko ,  KAWAKAMI, Eiryo ,  WATANABE, Shinji

IPC: C12N5/00 ,  C12N5/10 ,  C12N7/02 ,  C12N15/113

Abstract: The present invention provides cells which have a high ability to propagate influenza virus, are suitable for use in production of an influenza virus for preparing a vaccine, and are able to be cultured in vitro, and a method for producing an influenza virus using the cells. That is, the present invention provides cells for producing an influenza virus in which expression of one or more genes that encode proteins involved in an effect of suppressing influenza virus production in a cell is suppressed and the gene is at least one selected from the group including ACTG1 gene and the like, and a method for producing an influenza virus that includes infecting the cells for producing an influenza virus with an influenza virus and then culturing.