发明公开
- 专利标题: NUCLEIC ACID LIGANDS AND USES THEREFOR
- 专利标题(中): 核酸配和使用
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申请号: EP03778490.7申请日: 2003-11-05
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公开(公告)号: EP1560928A2公开(公告)日: 2005-08-10
- 发明人: STOCKLEY, Peter , ADAMS, Christopher , BUNKA, David , RAMBARAN, Roma , PHILLIPS, Simon , RADFORD, Sheena
- 申请人: THE UNIVERSITY OF LEEDS
- 申请人地址: Leeds, LS2 9JT GB
- 专利权人: THE UNIVERSITY OF LEEDS
- 当前专利权人: THE UNIVERSITY OF LEEDS
- 当前专利权人地址: Leeds, LS2 9JT GB
- 代理机构: Harrison Goddard Foote
- 优先权: GB0225833 20021106
- 国际公布: WO2004042083 20040521
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
The present invention relates to novel nucleic acid molecules or ligands or aptamers with affinities for specific target molecules, and uses of such molecules. The target molecules are fibrillar proteins in all forms of the protein that is to say its monomeric, pre-fibrillar, protofibrillar and mature fibrillar forms. The molecules of the present invention are therefore useful as diagnostic or therapeutic or screening agents, or as potential lead compounds for rationalised drug design.
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