公开(公告)号：EP1560928A2

公开(公告)日：2005-08-10

申请号：EP03778490.7

申请日：2003-11-05

申请人： THE UNIVERSITY OF LEEDS

发明人： STOCKLEY, Peter ,  ADAMS, Christopher ,  BUNKA, David ,  RAMBARAN, Roma ,  PHILLIPS, Simon ,  RADFORD, Sheena

IPC分类号： C12Q1/68

CPC分类号： C12N15/115 ,  C12N2310/16 ,  C12N2310/3517

摘要： The present invention relates to novel nucleic acid molecules or ligands or aptamers with affinities for specific target molecules, and uses of such molecules. The target molecules are fibrillar proteins in all forms of the protein that is to say its monomeric, pre-fibrillar, protofibrillar and mature fibrillar forms. The molecules of the present invention are therefore useful as diagnostic or therapeutic or screening agents, or as potential lead compounds for rationalised drug design.