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公开(公告)号：EP3161131B1
公开(公告)日：2020-02-19
申请号：EP15736012.4
申请日：2015-06-23
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公开(公告)号：EP2822603B1
公开(公告)日：2019-07-31
申请号：EP13709993.3
申请日：2013-03-07
发明人： SAHA, Sikha , JOSE, Gin , JHA, Animesh
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公开(公告)号：EP2869917B1
公开(公告)日：2018-03-21
申请号：EP13737651.3
申请日：2013-07-03
CPC分类号： B05C3/02 , A61K49/223 , B01J13/04 , B01J13/22 , B05D1/18
摘要： The present invention relates to methods and apparatus to provide coated microbubbles, particularly but not exclusively microbubbles at least partially coated with a component, for example a clinically active component. Systems of the present invention use electromagnetic fields to move microbubbles between streams of liquids in order to perform coating or washing steps.
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公开(公告)号：EP1320905B1
公开(公告)日：2017-11-15
申请号：EP01963213.2
申请日：2001-08-31
发明人： WARD, Ian, Macmillan , HUBBARD, Hugh, Vyvyan, St. Aubyn , CARR, Paul, Lambton , TYLDESLEY, W. F. Pelikon Unit 5
IPC分类号： H01M4/13 , H01M10/0525 , H01M10/0565 , H01M10/0585 , H01M6/40 , H01M4/04 , H01M6/16
CPC分类号： H01M4/0416 , H01M4/04 , H01M4/0404 , H01M4/0407 , H01M4/043 , H01M4/0435 , H01M4/13 , H01M6/162 , H01M6/40 , H01M10/0525 , H01M10/0565 , H01M10/0585 , H01M2300/0085 , Y02E60/122 , Y10T29/49108 , Y10T29/4911 , Y10T29/49112 , Y10T29/49114 , Y10T29/49115 , Y10T29/53135 , Y10T156/10 , Y10T428/31504
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公开(公告)号：EP3033178A1
公开(公告)日：2016-06-22
申请号：EP14723859.6
申请日：2014-05-08
发明人： WALTI, Christoph , SMITH, Alban Josiah , O'RORKE, Richard , DAVIES, Alexander Giles , WOOD, Christopher David
CPC分类号： B03C5/005 , B01L3/502761 , B01L2200/0652 , B01L2400/0424 , B01L2400/0436 , B01L2400/0439 , B03C5/02 , B03C5/022 , B03C2201/26
摘要： A method and apparatus for manipulating polarizable dielectric particles. The method includes positioning a liquid containing the particles above a surface of a piezoelectric material (2). The method also includes inducing a shear-horizontal surface acoustic wave in the piezoelectric material (2), thereby to form a time-varying non-uniform evanescent electric field extending into the liquid. The method further includes using the time-varying non-uniform evanescent electric field to apply a force to at least some of the particles (50, 52) by dielectrophoresis.
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公开(公告)号：EP2983689A1
公开(公告)日：2016-02-17
申请号：EP14716398.4
申请日：2014-04-08
IPC分类号： A61K38/04 , A61K31/728 , C07K11/00 , C08L5/08 , A61P19/00
CPC分类号： A61K47/6903 , A61K9/0019 , A61K9/0024 , A61K31/726 , A61K31/728 , A61K38/04 , A61K38/08 , A61K47/55 , A61M5/19 , C07K7/06 , C08L5/02 , C08L5/08 , A61K2300/00
摘要： Novel self-assembling peptide complexes comprising a charged peptide and a polysaccharide, methods of producing them and uses therefore are described. The novel self-assembling peptide complexes have particular utility in the restoration of biomechanical or biochemical function of a variety of biological tissues, for example and without limitation, in degenerated spinal discs, osteoarthritic joints, damaged cartilage, meniscus, ligaments, tendons, dental, ophthalmic and cardiovascular and blood vessel tissues. Methods of repairing and or restoring biomechanical or biochemical function of biological tissues and scaffolds for the support of cell growth are also described.
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公开(公告)号：EP2866647A1
公开(公告)日：2015-05-06
申请号：EP13734823.1
申请日：2013-07-01
CPC分类号： A61B5/05 , A61B5/04005 , A61B5/04007 , A61B5/04008 , A61B2562/0223 , G01R33/0023
摘要： A medical magnetometer (10) comprising one or more induction coils (2) for detecting a time varying magnetic field of a region of a subject's body, such as the heart. Each coil has a maximum outer diameter of 4 to 7 cm, and a configuration such that the ratio of the coil's length to its outer diameter is at least 0.5, and the ratio of the coil's inner diameter to its outer diameter is 0.5 or less. Each induction coil (2) is coupled to a respective detection circuit comprising a low impedance pre-ampiifier (3), a low pass filter (5), a notch filter (6) to remove line noise, and an averaging element (7). Each detection circuit produces an output signal (9) for use to analyse the time varying magnetic field of the region of the subject's body.
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公开(公告)号：EP2794906A1
公开(公告)日：2014-10-29
申请号：EP12813944.1
申请日：2012-12-21
IPC分类号： C12Q1/02 , G01N33/50 , G01N33/483 , C12M3/00
CPC分类号： G01N33/5005 , B01L3/5085 , C12M29/04 , C12M41/46 , C12Q1/02 , G01N21/03 , G01N21/293 , G01N21/78 , G01N33/4833 , G01N2021/0325 , G01N2021/0328
摘要： The present invention relates to an apparatus for, and methods of, assessing cell viability in a biological sample comprising cells or tissue. In particular the present invention provides quality assurance assays for complex biomaterials, especially but not exclusively cells derived from the pancreas, liver, kidney, lung, bone marrow and stem cells, for use in biomedical procedures. The present invention provides
inter alia methods of improving assessment of donor cell/tissue viability, methods of improving the success of donor cell/tissue transplant procedures, methods of assessing the functional properties of complex biological materials prior to their use in regenerative therapies and kits therefor.-
公开(公告)号：EP1523494B1
公开(公告)日：2009-12-23
申请号：EP03763994.5
申请日：2003-07-15
CPC分类号： A61L27/22 , C07K14/001
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公开(公告)号：EP1412506B1
公开(公告)日：2007-10-17
申请号：EP02745659.9
申请日：2002-07-19
发明人： BAKER, Alison, Leeds Institute for Biotechnolgy & , SLOCOMBE, Stephen, Leeds Institute for , GRAHAM, Ian Centre for Novel Agricultural Products
IPC分类号： C12N15/82
CPC分类号： C07K14/415 , C12N15/8209 , C12N15/8247
摘要： A nucleic acid which encodes a peroxisomal fatty acid transporter, uses thereof and a method of genetic manipulation of peroxisomal fatty acid transport and/or Metabolism. The nucleic acid and its products are especially for use in regulation of peroxisomal fatty acid transport in plant and in controlling the spectrum of fatty acids which can be utilised by the plant.
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