发明公开
- 专利标题: PROCESS FOR REDUCTIVE DEHALOGENATION
- 专利标题(中): VERFAHREN ZUR REDUKTIVEN DESHALOGENIERUNG
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申请号: EP04700528申请日: 2004-01-07
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公开(公告)号: EP1582513A4公开(公告)日: 2006-07-05
- 发明人: TANI YUICHIRO , NAKAYAMA KEIJI , SAKURATANI KENJI , SATO KOJI
- 申请人: DAIICHI SEIYAKU CO
- 专利权人: DAIICHI SEIYAKU CO
- 当前专利权人: DAIICHI SEIYAKU CO
- 优先权: JP2003001300 2003-01-07
- 主分类号: C07C67/317
- IPC分类号: C07C67/317 ; C07B61/00 ; C07C69/74
摘要:
A process for production of 2-fluorocyclopropane-1 -carboxylic esters, characterized by reacting a compound represented by the general formula (1) with a reducing agent in the presence of a phase transfer catalyst: (1) [wherein X is chloro, bromo, or iodo; and R1 is alkyl having 1 to 8 carbon atoms, aryl having 6 to 12 carbon atoms, alkenyl having 2 to 8 carbon atoms, or aralkyl composed of aryl having 6 to 12 carbon atoms and alkylene having 1 to 6 carbon atoms]. According to the process, the reaction time of dehalogenation can be remarkably shortened.
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