发明公开
EP1628623A2 METHOD FOR TREATING DISEASES USING HSP90-INHIBITING AGENTS IN COMBINATION WITH ENZYME INHIBITORS
审中-公开
方法与HSP90消炎药疾病的结合酶抑制剂治疗
- 专利标题： METHOD FOR TREATING DISEASES USING HSP90-INHIBITING AGENTS IN COMBINATION WITH ENZYME INHIBITORS
- 专利标题（中）： 方法与HSP90消炎药疾病的结合酶抑制剂治疗
-
申请号： EP04753673.5申请日： 2004-05-28
-
公开(公告)号： EP1628623A2公开(公告)日： 2006-03-01
- 发明人: JOHNSON, Robert, Jr. , ZHOU, Yiqing , MÜLLER, Thomas
- 申请人： Kosan Biosciences, Inc.
- 申请人地址： 3832 Bay Center Place Hayward, CA 94545 US
- 专利权人： Kosan Biosciences, Inc.
- 当前专利权人： Kosan Biosciences, Inc.
- 当前专利权人地址： 3832 Bay Center Place Hayward, CA 94545 US
- 代理机构： Roques, Sarah Elizabeth
- 优先权： US474906P 20030530; US856696 20040527
- 国际公布： WO2005000213 20050106
- 主分类号： A61K6/00
- IPC分类号： A61K6/00
摘要：
The present invention provides a method for treating cancer. The method involves the administration of an HSP90 inhibitor and an enzyme inhibitor, where the combined administration provides a synergistic effect. In one aspect of the invention, a method of treating cancer is provided where a subject is treated with a dose of an HSP90 inhibitor in one step and a dose of an enzyme inhibitor in another step. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an HSP90 inhibitor and subsequently treated with a dose of an enzyme inhibitor. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an enzyme inhibitor and subsequently treated with a dose of an HSP90 inhibitor.
信息查询
