发明公开
EP1641926A2 THERAPEUTIC USE OF LPI, A STAPHYLOCOCCAL LECTIN PATHWAY INHIBITOR IN INFLAMMATORY DISEASES
有权
LPI，LECTINWEGS的抑制剂葡萄球菌治疗用途AT点火疾病
- 专利标题： THERAPEUTIC USE OF LPI, A STAPHYLOCOCCAL LECTIN PATHWAY INHIBITOR IN INFLAMMATORY DISEASES
- 专利标题（中）： LPI，LECTINWEGS的抑制剂葡萄球菌治疗用途AT点火疾病
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申请号： EP04740883.6申请日： 2004-07-08
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公开(公告)号： EP1641926A2公开(公告)日： 2006-04-05
- 发明人: VAN WAMEL, Willem, Jan, Bastiaan , ROOIJAKKERS, Suzan, Huberdina, Maria , VAN KESSEL, Cornelis, Petrus, Maria , VAN STRIJP, Johannes, Antonius, Gerardus
- 申请人： UMC Utrecht Holding B.V.
- 申请人地址： Jenalaan 18a 3584 CK Utrecht NL
- 专利权人： UMC Utrecht Holding B.V.
- 当前专利权人： UMC Utrecht Holding B.V.
- 当前专利权人地址： Jenalaan 18a 3584 CK Utrecht NL
- 代理机构： Van Someren, Petronella F. H. M.
- 优先权： EP03077138 20030708
- 国际公布： WO2005005630 20050120
- 主分类号： C12N15/31
- IPC分类号： C12N15/31 ; C12N7/01 ; C12N15/63 ; C07K14/31 ; A61K39/085 ; A61K48/00 ; A61K39/40 ; G01N33/569 ; C12Q1/68 ; A61P29/00
摘要：
The invention relates to nucleic acid molecules encoding (poly)peptides having LPI (Lectin Pathway Inhibitor) activity, to recombinant vectors harboring such molecules, and the host cells carrying the vectors. The invention further relates to methods for preparing recombinant (poly)peptides having LPI activity and to the use of such recombinant (poly)peptides having LPI activity for diagnosis, prophylaxis and treatment, such as the treatment of inflammation reactions. In addition the invention provides therapeutic and diagnostic compositions comprising as the active ingredient the (poly)peptide having LPI activity.
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