发明公开
EP1648884A2 PYRAZOLYL-INDOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
审中-公开
PYRAZOLYLINDOLDERIVATE，作为激酶抑制剂的工作方法及其和药物组合物含
- 专利标题： PYRAZOLYL-INDOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
- 专利标题（中）： PYRAZOLYLINDOLDERIVATE，作为激酶抑制剂的工作方法及其和药物组合物含
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申请号： EP04763124.7申请日： 2004-07-08
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公开(公告)号： EP1648884A2公开(公告)日： 2006-04-26
- 发明人: BERTA, Daniela, Gavina , FORTE, Barbara , MANTEGANI, Sergio , VARASI, Mario , VIANELLO, Paola
- 申请人： Pharmacia Italia S.p.A.
- 申请人地址： Via Robert Koch 1.2 20152 Milano IT
- 专利权人： Pharmacia Italia S.p.A.
- 当前专利权人： Pharmacia Italia S.p.A.
- 当前专利权人地址： Via Robert Koch 1.2 20152 Milano IT
- 代理机构： Modiano, Micaela Nadia
- 优先权： US485406P 20030708
- 国际公布： WO2005005414 20050120
- 主分类号： C07D403/04
- IPC分类号： C07D403/04 ; A61K31/4155
摘要：
Pyrazolyl-indole derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
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