发明公开
- 专利标题： Vaccine for preventing and treating porcine progressive atrophic rhinitis
- 专利标题（中）： 疫苗预防和治疗猪进行性萎缩性鼻炎
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申请号： EP05017940.7申请日： 2005-08-18
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公开(公告)号： EP1657248A3公开(公告)日： 2006-05-24
- 发明人: Chien, Maw-Sheng , Liu, Cheng-I , Liao, Chih-Ming
- 申请人： National Chung-Hsing University
- 申请人地址： No. 250, Kuo Kuang Road South District 402 Taichung City TW
- 专利权人： National Chung-Hsing University
- 当前专利权人： National Chung-Hsing University
- 当前专利权人地址： No. 250, Kuo Kuang Road South District 402 Taichung City TW
- 代理机构： Roberts, Michael Austin
- 优先权： CN200410057590 20040820
- 主分类号： C07K14/285
- IPC分类号： C07K14/285 ; A61K39/102 ; C12N15/09
摘要：
The present invention relates to an animal vaccine directed to progressive atrophic rhinitis (PAR), comprising at least two fragmens of recombinant subunit Pasteurella multocida toxins (rsPMT) capable of eliciting the production of antibodies against Pasteurella multocida associated with PAR, said fragments each having an amino acid sequence that substantially corresponds to the 2-486, 486-986 or 986-1281 amino acid residues of Pasteurella multocida toxin (PMT), respectively. Also disclosed is a multivalent animal vaccine, comprising said fragments as active components against PAR, and at least a pathogenic antigen or epitope thereof associated with other animal disease(s), such as inactivated gE-deleted Pseudorabies virus.
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