发明授权
- 专利标题: PROTEASOME INHIBITORS AND METHODS OF USING THE SAME
- 专利标题(中): 蛋白酶体抑制剂及其用途
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申请号: EP04781132.8申请日: 2004-08-13
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公开(公告)号: EP1658255B1公开(公告)日: 2009-02-18
- 发明人: CHATTERJEE, Sankar , IQBAL, Mohamed , MENTA, Ernesto , OLIVA, Ambrogio
- 申请人: CEPHALON, INC.
- 申请人地址: 41 Moores Road, P.O.Box 4011 Frazer, PA 19355 US
- 专利权人: CEPHALON, INC.
- 当前专利权人: CEPHALON, INC.
- 当前专利权人地址: 41 Moores Road, P.O.Box 4011 Frazer, PA 19355 US
- 代理机构: Hallybone, Huw George
- 优先权: US495364P 20030814; US918610 20040812
- 国际公布: WO2005016859 20050224
- 主分类号: C07C29/00
- IPC分类号: C07C29/00
摘要:
The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
公开/授权文献
- EP1658255A2 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME 公开/授权日:2006-05-24
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