发明授权
- 专利标题: SUBSTITUIERTE THIENOIMIDAZOLE, VERFAHREN ZU IHRER HERSTELLUNG, IHRE VERWENDUNG ALS MEDIKAMENT ODER DIAGNOSTIKUM SOWIE SIE ENTHALTENDE MEDIKAMENTE
- 专利标题(英): Substituted thienoimidazoles, method for production and use thereof as medicament or diagnostic and medicaments comprising the same
- 专利标题(中): 取代的噻吩并,工艺所周之,及其作为药物或诊断和含有药物
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申请号: EP04764791.2申请日: 2004-09-03
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公开(公告)号: EP1664058B1公开(公告)日: 2007-11-14
- 发明人: LANG, Hans-Jochen , HEINELT, Uwe , WIRTH, Klaus , LICHER, Thomas
- 申请人: Sanofi-Aventis Deutschland GmbH
- 申请人地址: Brüningstrasse 50 65929 Frankfurt am Main DE
- 专利权人: Sanofi-Aventis Deutschland GmbH
- 当前专利权人: Sanofi-Aventis Deutschland GmbH
- 当前专利权人地址: Brüningstrasse 50 65929 Frankfurt am Main DE
- 优先权: DE10341240 20030908
- 国际公布: WO2005026173 20050324
- 主分类号: C07D495/04
- IPC分类号: C07D495/04 ; A61K31/4188 ; A61P1/00 ; A61P11/00
摘要:
The invention relates to substituted thienoimidazoles of formula (I) or (II), where R1 to R4 have the meanings given in the claims. Medicaments comprising compounds of this type are useful for the prevention or treatment of diverse diseases. The compounds find application, amongst other things, for the treatment of breathing disorders and snoring, to improve the breathing process, for treatment of chronic and acute diseases of the kidney and the intestine, diseases caused by ischaemic and/or reperfusion events, proliferative or fibrotic diseases, for the treatment or prophylaxis of diseases of the central nervous system, lipometabolism, diabetes, blood clotting and parasitic attack.
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