发明公开
- 专利标题: Recombinant adenovirus comprising a chimeric penton base protein
- 专利标题(中): 具有嵌合五邻体基底的重组腺病毒
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申请号: EP06003302.4申请日: 1995-08-07
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公开(公告)号: EP1679376A3公开(公告)日: 2006-08-16
- 发明人: Wickham, Thomas J. , Kovesdi, Imre , Brough, Douglas E. , McVey, Duncan L. , Bruder, Joseph T.
- 申请人: GENVEC, INC.
- 申请人地址: 12111 Parklawn Drive Rockville, MD 20852 US
- 专利权人: GENVEC, INC.
- 当前专利权人: GENVEC, INC.
- 当前专利权人地址: 12111 Parklawn Drive Rockville, MD 20852 US
- 代理机构: Hoeger, Stellrecht & Partner Patentanwälte
- 优先权: US303162 19940908
- 主分类号: C12N15/86
- IPC分类号: C12N15/86 ; C12N15/87 ; C12N7/01 ; C12N15/34 ; A61K48/00
摘要:
A recombinant adenovirus comprising a chimeric penton base protein, wherein an RGD amino acid sequence is deleted from the penton base protein, a method of gene therapy involving the use of such adenovirus, and adenoviral transfer vectors for the generation of such recombinant adenovirus are provided.
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