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公开(公告)号：EP1679376A3
公开(公告)日：2006-08-16
申请号：EP06003302.4
申请日：1995-08-07
申请人： GENVEC, INC.
CPC分类号： C12N15/87 , A61K48/00 , C07K14/005 , C07K14/70546 , C07K2319/00 , C12N7/00 , C12N15/86 , C12N2710/10322 , C12N2710/10343 , C12N2710/10345 , C12N2710/14043 , C12N2710/14143 , C12N2810/40 , C12N2810/405 , C12N2810/60 , C12N2810/6018 , C12N2810/80 , C12N2810/855 , C12N2810/856 , C12N2810/859
摘要： A recombinant adenovirus comprising a chimeric penton base protein, wherein an RGD amino acid sequence is deleted from the penton base protein, a method of gene therapy involving the use of such adenovirus, and adenoviral transfer vectors for the generation of such recombinant adenovirus are provided.
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2.发明公开Recombinant adenovirus comprising a chimeric penton base protein 失效Rekombinanter Adenovirus，der einechimärePenton-Base aufweist
公开(公告)号：EP1679376A2
公开(公告)日：2006-07-12
申请号：EP06003302.4
申请日：1995-08-07
申请人： GENVEC, INC.
CPC分类号： C12N15/87 , A61K48/00 , C07K14/005 , C07K14/70546 , C07K2319/00 , C12N7/00 , C12N15/86 , C12N2710/10322 , C12N2710/10343 , C12N2710/10345 , C12N2710/14043 , C12N2710/14143 , C12N2810/40 , C12N2810/405 , C12N2810/60 , C12N2810/6018 , C12N2810/80 , C12N2810/855 , C12N2810/856 , C12N2810/859
摘要： A recombinant adenovirus comprising a chimeric penton base protein, wherein an RGD amino acid sequence is deleted from the penton base protein, a method of gene therapy involving the use of such adenovirus, and adenoviral transfer vectors for the generation of such recombinant adenovirus are provided.
摘要翻译： 提供了一种重组腺病毒，其包含嵌合五羟色胺基蛋白，其中从五羟基蛋白缺失RGD氨基酸序列，涉及使用这种腺病毒的基因治疗方法和用于产生这种重组腺病毒的腺病毒转移载体。
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3.发明公开Complementary adenoviral vector systems and cell lines 失效Komplementäreadenovirale Vektor-Systeme und Zelllinien
公开(公告)号：EP1548118A2
公开(公告)日：2005-06-29
申请号：EP05005691.0
申请日：1995-06-07
申请人： GENVEC, INC.
IPC分类号： C12N15/861 , C07K14/075 , C12N15/34 , A61K48/00 , C07K14/47 , C12N5/10 , C12N7/01 , C12N15/12
CPC分类号： C12N7/00 , A61K38/00 , A61K48/00 , A61K2039/5256 , C07K14/005 , C07K14/4712 , C12N15/86 , C12N2710/10322 , C12N2710/10343 , C12N2710/10352 , C12N2810/60 , C12N2810/6081 , C12N2830/002 , C12N2830/85 , C12N2840/20 , C12N2840/203 , C12N2840/44 , Y10S977/799
摘要： The present invention provides multiply deficient adenoviral vectors and complementing cell lines. Also provided are recombinants of the multiply deficient adenoviral vectors and a therapeutic method, particularly relating to gene therapy, vaccination, and the like, involving the use of such recombinants.
摘要翻译： 本发明提供多重缺陷型腺病毒载体和补体细胞系。 还提供了多重缺陷型腺病毒载体的重组体和涉及使用这种重组体的治疗方法，特别是与基因治疗，疫苗接种等相关的治疗方法。
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