发明公开
EP1682570A4 A BINDING MOTIF AND METHODS OF REGULATING CELL FUNCTION
审中-公开
BINDUNGSMOTIV UND VERFAHREN ZUR STEUERUNG DER ZELLFUNKTION
- 专利标题： A BINDING MOTIF AND METHODS OF REGULATING CELL FUNCTION
- 专利标题（中）： BINDUNGSMOTIV UND VERFAHREN ZUR STEUERUNG DER ZELLFUNKTION
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申请号： EP04789618申请日： 2004-10-27
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公开(公告)号： EP1682570A4公开(公告)日： 2006-12-06
- 发明人: GUTHRIDGE MARK , RAMSHAW HAYLEY , STOMSKI FRANK , LOPEZ ANGEL
- 申请人： MEDVET SCIENCE PTY LTD
- 专利权人： MEDVET SCIENCE PTY LTD
- 当前专利权人： MEDVET SCIENCE PTY LTD
- 优先权： AU2003905932 2003-10-27
- 主分类号： C07K2/00
- IPC分类号： C07K2/00 ; A61K38/00 ; A61K38/19 ; A61K38/20 ; A61P35/00 ; A61P43/00 ; C07K5/113 ; C07K7/06 ; C07K14/435 ; C07K14/71 ; C07K14/715
摘要：
The present invention relates to a binding motif and methods of regulating cell function which methods target a single amino acid residue preferably a Tyr in a binding motif equivalent to a motif of the common beta chain (ßc) of the GM-CSF/IL-3/IL-5 receptor. Preferably, the cell functions affect cell survival and proliferation in cells. The methods can be used for treatments of conditions relating to cell survival and proliferation and can be used to expand progenitor cells, for instance, for transplantation purposes.
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