发明公开
- 专利标题： SYNTHETIC PROCESS
- 专利标题（中）： 合成工艺
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申请号： EP04814139.4申请日： 2004-12-10
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公开(公告)号： EP1694683A2公开(公告)日： 2006-08-30
- 发明人: SWAMINATHAN, Shankar , GAVAI, Ashvinikumar V. , FAN, Junying , PATEL, Bharat P. , NORRIS, Derek J. , CORBETT, Richard Michael , ZHENG, Bin
- 申请人： Bristol-Myers Squibb Company
- 申请人地址： P.O. Box 4000, Route 206 and Province Line Road Princeton, NJ 08543-4000 US
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： P.O. Box 4000, Route 206 and Province Line Road Princeton, NJ 08543-4000 US
- 代理机构： Vossius & Partner
- 优先权： US529347P 20031212; US8719 20041209
- 国际公布： WO2005058245 20050630
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/53 ; A61P35/00
摘要：
The present invention provides a process for preparing compounds of formula (I) ['insert chemical structure here'](I)or a pharmaceutically acceptable salt thereof. The compounds prepared by the process of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.
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