发明授权
- 专利标题： PYRROLOTRIAZINE COMPOUNDS AS KINASE INHIBITORS
- 专利标题（中）： PYRROLOTRIAZINVERBINDUNGEN作为激酶抑制剂
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申请号： EP04815269.8申请日： 2004-12-23
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公开(公告)号： EP1699797B1公开(公告)日： 2009-09-23
- 发明人: FINK, Brian, E. , GAVAI, Ashvinikumar, V. , VITE, Gregory, D. , CHEN, Ping , MASTALERZ, Harold , NORRIS, Derek, J. , TOKARSKI, John, S. , ZHAO, Yufen , HAN, Wen-Ching
- 申请人： Bristol-Myers Squibb Company
- 申请人地址： Route 206 and Province Line Road Princeton, NJ 05843-4000 US
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： Route 206 and Province Line Road Princeton, NJ 05843-4000 US
- 代理机构： Vossius & Partner
- 优先权： US533335P 20031229
- 国际公布： WO2005066176 20050721
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; C07D519/00 ; A61K31/53 ; A61P35/00
摘要：
The present invention provides compounds of formula (I); and pharmaceutically acceptable salts thereof. The formula (I) compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula (I) compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
公开/授权文献
- EP1699797A1 PYRROLOTRIAZINE COMPOUNDS AS KINASE INHIBITORS 公开/授权日：2006-09-13
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