发明公开
- 专利标题: VIRAL POLYMERASE INHIBITORS
- 专利标题(中): 病毒聚合酶抑制剂
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申请号: EP05714457.8申请日: 2005-02-18
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公开(公告)号: EP1718608A1公开(公告)日: 2006-11-08
- 发明人: TSANTRIZOS, Youla, S. , CHABOT, Catherine , BEAULIEU, Pierre , BROCHU, Christian , POIRIER, Martin , STAMMERS, Timothy, A. , THAVONEKHAM, Bounkham , RANCOURT, Jean
- 申请人: Boehringer Ingelheim International GmbH , Boehringer Ingelheim Pharma GmbH & Co. KG
- 申请人地址: CD Patents, Binger Strasse 173 55216 Ingelheim DE
- 专利权人: Boehringer Ingelheim International GmbH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人: Boehringer Ingelheim International GmbH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人地址: CD Patents, Binger Strasse 173 55216 Ingelheim DE
- 代理机构: Hammann, Heinz
- 优先权: US546213P 20040220
- 国际公布: WO2005080388 20050901
- 主分类号: C07D201/00
- IPC分类号: C07D201/00
摘要:
An enantiomer, diastereoisomer or tautomer of a compound, represented by formula (I): wherein either A or B is nitrogen and the other B or A is C, and the radicals R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein, or a salt or ester thereof as viral polymerase inhibitors. The compound is used as an inhibitor of RNA dependent RNA polymerases, particularly those viral polymerases within the Flaviviridae family, more particularly to HCV polymerase.
公开/授权文献
- EP1718608B1 VIRAL POLYMERASE INHIBITORS 公开/授权日:2013-07-17
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