发明公开
EP1751282A2 PRODUCTION OF HOST CELLS CONTAINING MUTIPLE INTEGRATING VECTORS BY SERIAL TRANSDUCTION
审中-公开
宿主细胞多个生产整合载体包含由串行转导
- 专利标题： PRODUCTION OF HOST CELLS CONTAINING MUTIPLE INTEGRATING VECTORS BY SERIAL TRANSDUCTION
- 专利标题（中）： 宿主细胞多个生产整合载体包含由串行转导
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申请号： EP05705678.0申请日： 2005-01-14
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公开(公告)号： EP1751282A2公开(公告)日： 2007-02-14
- 发明人: BLECK, Gregory, T. , BREMEL, Robert, D. , MILLER, Linda, U.
- 申请人： Gala Design, Inc.
- 申请人地址： 8137 Forsythia Street Middleton, WI 53562 US
- 专利权人： Gala Design, Inc.
- 当前专利权人： Gala Design, Inc.
- 当前专利权人地址： 8137 Forsythia Street Middleton, WI 53562 US
- 代理机构： Glawe, Delfs, Moll
- 优先权： US759315 20040116
- 国际公布： WO2005072129 20050811
- 主分类号： C12N15/09
- IPC分类号： C12N15/09
摘要：
The present invention relates to the production of proteins in host cells, and more particularly to host cells containing multiple integrated copies of an integrating vector comprising an exogenous gene and methods of making such host cells by serial transduction or transfection. The present invention further provides methods of expressing increased levels of protein in host cells using such vectors.
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