发明公开
EP1796669A2 AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
有权
氨基哌啶，ALS二肽基肽酶IV抑制剂为糖尿病治疗或预防
- 专利标题： AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
- 专利标题（中）： 氨基哌啶，ALS二肽基肽酶IV抑制剂为糖尿病治疗或预防
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申请号： EP05802868.9申请日： 2005-09-27
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公开(公告)号： EP1796669A2公开(公告)日： 2007-06-20
- 发明人: COX, Jason, M. , EDMONDSON, Scott, D. , HARPER, Bart , WEBER, Ann, E.
- 申请人： Merck & Co., Inc.
- 申请人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 代理机构： Buchan, Gavin MacNicol
- 优先权： US615478P 20041001
- 国际公布： WO2006039325 20060413
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; A61K31/495 ; A61K31/50 ; A61K31/505 ; A61K31/525 ; C07D237/26 ; C07D239/00 ; C07D239/70 ; C07D239/72 ; C07D241/00 ; C07D241/36 ; C07D401/04 ; C07D471/04 ; C07D491/04 ; C07D487/00
摘要：
The present invention is directed to novel substituted aminopiperidines which are inhibitors of the dipeptidyl peptidase-IV enzyme ('DPP-IV inhibitors') and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
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