发明公开
EP1801106A2 New spirotricyclic derivatives and their use as phosphodiesterase-7 inhibitors
审中-公开
新的螺环三环衍生物及其作为磷酸二酯酶-7抑制剂的用途
- 专利标题： New spirotricyclic derivatives and their use as phosphodiesterase-7 inhibitors
- 专利标题（中）： 新的螺环三环衍生物及其作为磷酸二酯酶-7抑制剂的用途
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申请号： EP07104642.9申请日： 2002-03-18
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公开(公告)号： EP1801106A2公开(公告)日： 2007-06-27
- 发明人: Bernardelli, Patrick , Ducrot, Pierre , Lorthiois, Edwige , Vergne, Fabrice
- 申请人： Warner-Lambert Company LLC
- 申请人地址： 235 East 42nd Street New York, NY 10017 US
- 专利权人： Warner-Lambert Company LLC
- 当前专利权人： Warner-Lambert Company LLC
- 当前专利权人地址： 235 East 42nd Street New York, NY 10017 US
- 代理机构： Duncan, Garreth Andrew
- 优先权： PCT/EP01/03355 20010321
- 主分类号： C07D239/70
- IPC分类号： C07D239/70 ; C07D401/04 ; C07D403/04 ; A61K31/527 ; A61P29/00 ; C07D405/12 ; C07D413/12 ; C07D401/12
摘要：
The invention provides compounds which are PDE7 inhibitors, having the following formula (I), (II) and (III), in which X 1 , X 2 , X 3 , X 4 , X, Y, Z, A and Z 1 are as defined in the description, methods for preparing them and their use for the treatment of disorders for which therapy by a PDE7 inhibitor is relevant.
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