发明公开
EP1802286A1 SUSTAINED DRUG RELEASE COMPOSITION DEMONSTRATING AN ASCENDING ZERO ORDER RELEASE PATTERN, METHODS OF MANUFACTURING SUCH A COMPOSITION
有权
与上升的零级释放时滞PATTERN释放药物成分; 用于制备这种组合物“
- 专利标题： SUSTAINED DRUG RELEASE COMPOSITION DEMONSTRATING AN ASCENDING ZERO ORDER RELEASE PATTERN, METHODS OF MANUFACTURING SUCH A COMPOSITION
- 专利标题（中）： 与上升的零级释放时滞PATTERN释放药物成分; 用于制备这种组合物“
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申请号： EP05779051.1申请日： 2005-08-02
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公开(公告)号： EP1802286A1公开(公告)日： 2007-07-04
- 发明人: CASADEVALL, Gemma , SUBRAMANIAN, Ramkumar , BARCLAY, Brian , ALLPHIN, Clark , SHIVANAND, Padmaja , YAM, Noymi, V.
- 申请人： ALZA CORPORATION
- 申请人地址： Alza Plaza, 1900 Charleston Road Mountain View, CA 94043 US
- 专利权人： ALZA CORPORATION
- 当前专利权人： ALZA CORPORATION
- 当前专利权人地址： Alza Plaza, 1900 Charleston Road Mountain View, CA 94043 US
- 代理机构： Williams, Paul Edwin
- 优先权： US599126P 20040804
- 国际公布： WO2006017537 20060216
- 主分类号： A61K9/50
- IPC分类号： A61K9/50 ; A61K9/20
摘要：
Disclosed are dosage forms and methods for sustained release of a drug including : a delay layer comprising a polymeric matrix, and microencapsulated drug, wherein the delay layer is substantially free of non-microencapsulated drug; and a second layer including a polymeric matrix, and non-microencapsulated drug matrix; wherein the second layer is located adjacent to the delay layer.
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