发明公开
- 专利标题： POLYMORPH FORM OF IRBESARTAN
- 专利标题（中）： IRBESARTAN的多态性
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申请号： EP05802257.5申请日： 2005-11-09
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公开(公告)号： EP1812422A1公开(公告)日： 2007-08-01
- 发明人: ANTONCIC, Ljubomir
- 申请人： LEK Pharmaceuticals d.d.
- 申请人地址： Verovskova 57 1526 Ljubljana SI
- 专利权人： LEK Pharmaceuticals d.d.
- 当前专利权人： LEK Pharmaceuticals d.d.
- 当前专利权人地址： Verovskova 57 1526 Ljubljana SI
- 代理机构： Skulj, Primoz
- 优先权： SI200400308 20041111
- 国际公布： WO2006050923 20060518
- 主分类号： C07D403/10
- IPC分类号： C07D403/10 ; A61K31/415
摘要：
New form of irbesartan having favourable chargeability is prepared from the alcoholic/etheric or ketonic solution of irbesartan after slow cooling with sporadic or light agitation and alternatively new crystalline form of an acid addition salt of irbesartan is prepared from the aqueous solution of a sodium salt of irbesartan after strongly acidifying aforesaid solution and subsequently adjusting pH with an alkali. Those are used in manufacturing a pharmaceutical composition.
公开/授权文献
- EP1812422B1 POLYMORPH FORM OF IRBESARTAN 公开/授权日：2013-12-25
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