发明公开
- 专利标题: COMPOUNDS AND THERAPEUTICAL USE THEREOF
- 专利标题(中): 化合物及其治疗用途
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申请号: EP06717281.7申请日: 2006-01-03
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公开(公告)号: EP1833482A2公开(公告)日: 2007-09-19
- 发明人: CAI, Sui Xiong , ANDERSON, Mark B. , WILLARDSEN, Adam , SIRISOMA, Nilantha Sudath , ZHANG, Hong , SUZUKI, Kazuyuki
- 申请人: MYRIAD GENETICS, INC. , Cytovia, Inc.
- 申请人地址: 320 Wakara Way Salt Lake City, Utah 84108 US
- 专利权人: MYRIAD GENETICS, INC.,Cytovia, Inc.
- 当前专利权人: MYRIAD GENETICS, INC.,Cytovia, Inc.
- 当前专利权人地址: 320 Wakara Way Salt Lake City, Utah 84108 US
- 代理机构: Adam, Holger
- 优先权: US641260P 20050103
- 国际公布: WO2006074147 20060713
- 主分类号: A61K31/50
- IPC分类号: A61K31/50 ; A61K31/519 ; A61K31/517 ; C07D239/72 ; C07D239/00 ; C07D241/04 ; C07D265/12 ; C07D321/00 ; C07D401/00 ; C07D403/00 ; C07D498/00
摘要:
Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
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