发明公开
- 专利标题: THIOPHENE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES
- 专利标题(中): 噻吩炎症和免疫系统相关申请
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申请号: EP06719650申请日: 2006-01-25
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公开(公告)号: EP1846388A4公开(公告)日: 2011-12-07
- 发明人: SUN LIJUN , CHEN SHOUJUN , JIANG JUN , XIA ZHI-QIANG , XIE YU , YU CHIH-YI
- 申请人: SYNTA PHARMACEUTICALS CORP
- 专利权人: SYNTA PHARMACEUTICALS CORP
- 当前专利权人: SYNTA PHARMACEUTICALS CORP
- 优先权: US64677205 2005-01-25
- 主分类号: C07D333/10
- IPC分类号: C07D333/10 ; A61K31/381 ; A61K31/4427 ; C07D333/20 ; C07D333/38 ; C07D409/04 ; C07D409/12 ; C07D409/14 ; C07D413/10 ; C07D413/14 ; C07D417/14
摘要:
The invention relates to compounds of structural formulas (I) and (XVI): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein X1, X2, Z, L, L2, R1, R2, R3, R21, n, q, and t are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
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