公开(公告)号：EP1848435A4

公开(公告)日：2010-09-29

申请号：EP06719652

申请日：2006-01-25

申请人： SYNTA PHARMACEUTICALS CORP

发明人： SUN LIJUN ,  CHEN SHOUJUN ,  JIANG JUN ,  YU CHIH-YI

IPC分类号： A61K31/4965 ,  A61K31/497 ,  A61K31/50 ,  A61K31/505 ,  A61P29/00 ,  A61P37/00 ,  C07D239/02 ,  C07D401/00 ,  C07D403/00 ,  C07D405/00 ,  C07D409/00 ,  C07D411/00 ,  C07D413/00 ,  C07D417/00 ,  C07D419/00

CPC分类号： C07D241/20 ,  A61K31/495 ,  A61K31/4965 ,  A61K31/497 ,  A61K31/50 ,  A61K31/505 ,  C07D401/12 ,  C07D401/14 ,  C07D403/10 ,  C07D405/14 ,  C07D413/10 ,  C07D413/14 ,  C07D417/14

摘要： The invention relates to compounds of structural formula (I) and structural formula (VI): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein R, R1, R2, Z, L, and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.

公开(公告)号：EP1651232A4

公开(公告)日：2007-06-06

申请号：EP04786102

申请日：2004-07-22

申请人： SYNTA PHARMACEUTICALS CORP

发明人： XIE YU ,  HOLMQVIST MATS ,  MAHIOU JEROME ,  ONO MITSUNORI ,  SUN LIJUN ,  CHEN SHOUJUN ,  ZHANG SHIJIE ,  JIANG JUN ,  CHIMMMANAMADA DINESH ,  YU CHIH-YI

IPC分类号： A61K31/535 ,  A61K31/35 ,  A61K31/381 ,  A61K31/40 ,  A61K31/41 ,  A61K31/415 ,  A61K31/4196 ,  A61K31/42 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/724 ,  A61P20060101 ,  A61P25/00 ,  A61P27/00 ,  A61P29/00 ,  A61P37/00 ,  C07D20060101

CPC分类号： C07C233/66 ,  A61K31/40 ,  A61K31/41 ,  A61K31/415 ,  A61K31/42 ,  A61K31/535 ,  C07C237/42 ,  C07D213/81 ,  C07D231/14 ,  C07D239/28 ,  C07D263/34 ,  C07D277/56 ,  C07D285/06 ,  C07D333/38

摘要： The invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein X, Y, A, Z, L and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions and immune disorders.

公开(公告)号：EP1846388A4

公开(公告)日：2011-12-07

申请号：EP06719650

申请日：2006-01-25

申请人： SYNTA PHARMACEUTICALS CORP

发明人： SUN LIJUN ,  CHEN SHOUJUN ,  JIANG JUN ,  XIA ZHI-QIANG ,  XIE YU ,  YU CHIH-YI

IPC分类号： C07D333/10 ,  A61K31/381 ,  A61K31/4427 ,  C07D333/20 ,  C07D333/38 ,  C07D409/04 ,  C07D409/12 ,  C07D409/14 ,  C07D413/10 ,  C07D413/14 ,  C07D417/14

CPC分类号： C07D333/38 ,  A61K31/381 ,  A61K31/4427 ,  A61K31/4436 ,  A61K31/444 ,  C07D333/20 ,  C07D409/04 ,  C07D409/12 ,  C07D409/14 ,  C07D413/10 ,  C07D413/14 ,  C07D417/14

摘要： The invention relates to compounds of structural formulas (I) and (XVI): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein X1, X2, Z, L, L2, R1, R2, R3, R21, n, q, and t are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.

公开(公告)号：EP1653968A4

公开(公告)日：2006-09-06

申请号：EP04779033

申请日：2004-07-22

申请人： SYNTA PHARMACEUTICALS CORP

发明人： XIE YU ,  HOLMQVIST MATS ,  MAHIOU JEROME ,  ONO MITSONORI ,  SUN LIJUN ,  CHEN SHOUJUN ,  ZHANG SHIJIE ,  JIANG JUN ,  CHINMMANAMADA DINESH ,  FLEIG ANDREA ,  YU CHIH-YI

IPC分类号： A61K31/535 ,  A61K31/35 ,  A61K31/381 ,  A61K31/40 ,  A61K31/41 ,  A61K31/415 ,  A61K31/4196 ,  A61K31/42 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/724 ,  A61P20060101 ,  A61P27/00 ,  C07D20060101

CPC分类号： C07C233/66 ,  A61K31/40 ,  A61K31/41 ,  A61K31/415 ,  A61K31/42 ,  A61K31/535 ,  C07C237/42 ,  C07D213/81 ,  C07D231/14 ,  C07D239/28 ,  C07D263/34 ,  C07D277/56 ,  C07D285/06 ,  C07D333/38

摘要： The invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein X, Y, A, Z, L and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions and immune disorders.