Invention Publication
EP1860180A1 METHOD FOR AMPLIFICATION OF ENDOTHELIAL PROGENITOR CELL IN VITRO
审中-公开
VERFAHREN ZUR AMPLIFIKATION EINER内皮素激素
- Patent Title: METHOD FOR AMPLIFICATION OF ENDOTHELIAL PROGENITOR CELL IN VITRO
- Patent Title (中): VERFAHREN ZUR AMPLIFIKATION EINER内皮素激素
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Application No.: EP06714935.1Application Date: 2006-02-22
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Publication No.: EP1860180A1Publication Date: 2007-11-28
- Inventor: ASAHARA, Takayuki,c/oDept.Reg.Med., Inst.Bio.Res. , MASUDA, Haruchika
- Applicant: Foundation for Biomedical Research and Innovation , TOKAI UNIVERSITY EDUCATIONAL SYSTEM
- Applicant Address: 2-2, Minatojimaminamimachi Chuo-ku Kobe-shi Hyogo 6500047 JP
- Assignee: Foundation for Biomedical Research and Innovation,TOKAI UNIVERSITY EDUCATIONAL SYSTEM
- Current Assignee: Foundation for Biomedical Research and Innovation,TOKAI UNIVERSITY EDUCATIONAL SYSTEM
- Current Assignee Address: 2-2, Minatojimaminamimachi Chuo-ku Kobe-shi Hyogo 6500047 JP
- Agency: Duckworth, Timothy John
- Priority: JP2005047816 20050223
- International Announcement: WO2006090882 20060831
- Main IPC: C12N5/00
- IPC: C12N5/00 ; A61K35/12 ; A61P9/10 ; C12N5/06
Abstract:
The present invention provides a method for expanding an endothelial progenitor cell in vitro. More particularly, the present invention provides a method for culturing a hemangioblast comprising incubating a hemangioblast in a serum-free culture medium containing one or more factors selected from the group consisting of stem cell growth factor, interleukin-6, FMS-like tyrosine kinase 3 and thrombopoietin, and a vascular endothelial cell produced by the method; and a serum-free culture medium containing one or more factors selected from the group consisting of stem cell growth factor, interleukin-6, FMS-like tyrosine kinase 3 and thrombopoietin, and a kit for the preparation of the serum-free culture medium and the like.
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