发明公开
- 专利标题: ANTIBAKTERIELLE AMID-MAKROZYKLEN V
- 专利标题(英): Antibacterial amide-macrocycles v
- 专利标题(中): ANTIBAKTERIELLE阿米德 - MAKROZYKLEN V
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申请号: EP06723614.1申请日: 2006-03-22
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公开(公告)号: EP1869068A1公开(公告)日: 2007-12-26
- 发明人: ENDERMANN, Rainer , EHLERT, Kerstin , RADDATZ, Siegfried , MICHELS, Martin , CANCHO-GRANDE, Yolanda , WEIGAND, Stefan , FISCHER, Karin
- 申请人: AiCuris GmbH & Co. KG
- 申请人地址: Friedrich-Ebert-Strasse 475 42117 Wuppertal DE
- 专利权人: AiCuris GmbH & Co. KG
- 当前专利权人: AiCuris GmbH & Co. KG
- 当前专利权人地址: Friedrich-Ebert-Strasse 475 42117 Wuppertal DE
- 代理机构: Weller, Wolfgang
- 优先权: DE102005014245 20050330
- 国际公布: WO2006103015 20061005
- 主分类号: C07K5/10
- IPC分类号: C07K5/10 ; C07K5/08 ; C07K5/02 ; C07K7/02 ; A61K38/07 ; A61K38/06 ; A61K38/08 ; A61K38/03
摘要:
The invention relates to antibacterial amide-macrocycles of formula (I), in which R26 represents hydrogen, halogen, amino or methyl, R7 represents a group of formula (II), (III), (IV) or (V), where R1 represents hydrogen or hydroxy and * stands for the bonding point on the carbon atom, and R2 represents hydrogen or methyl. The invention also relates to a method for producing said macrocycles, to their use for the treatment and/or prophylaxis of diseases and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infections.
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