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公开(公告)号：EP1866291A1
公开(公告)日：2007-12-19
申请号：EP06723578.8
申请日：2006-03-21
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , RADDATZ, Siegfried , MICHELS, Martin , CANCHO-GRANDE, Yolanda , WEIGAND, Stefan , FISCHER, Karin
IPC分类号： C07D245/04 , A61P31/04 , C07K5/06 , C07K5/08 , C07K5/10
CPC分类号： C07K5/0202 , C07D245/04 , C07K5/0812 , C07K5/1016 , C07K7/02 , C07K7/06
摘要： The invention concerns antibacterial amide macrocycles , methods for producing same, their use for treating and/or preventing diseases, as well as their use for producing drugs for treating and/or preventing diseases, in particular bacterial infections.
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公开(公告)号：EP1866291B1
公开(公告)日：2009-07-15
申请号：EP06723578.8
申请日：2006-03-21
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , RADDATZ, Siegfried , MICHELS, Martin , CANCHO-GRANDE, Yolanda , WEIGAND, Stefan , FISCHER, Karin
IPC分类号： C07D245/04 , A61P31/04 , C07K5/06 , C07K5/08 , C07K5/10
CPC分类号： C07K5/0202 , C07D245/04 , C07K5/0812 , C07K5/1016 , C07K7/02 , C07K7/06
摘要： The invention concerns antibacterial amide macrocycles , methods for producing same, their use for treating and/or preventing diseases, as well as their use for producing drugs for treating and/or preventing diseases, in particular bacterial infections.
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公开(公告)号：EP1697400B1
公开(公告)日：2011-05-25
申请号：EP04801192.8
申请日：2004-12-02
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , RADDATZ, Siegfried , CANCHO GRANDE, Yolanda , MICHELS, Martin , WEIGAND, Stefan , ADELT, Isabelle , LAMPE, Thomas
CPC分类号： C07K7/06 , C07K5/0812 , C07K5/1016
摘要： The invention relates to biphenyl-substituted antibacterial macrocycles, to methods for their production, to their use in the treatment and/or prophylaxis of diseases, in addition to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infections.
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公开(公告)号：EP1697400A1
公开(公告)日：2006-09-06
申请号：EP04801192.8
申请日：2004-12-02
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , RADDATZ, Siegfried , CANCHO GRANDE, Yolanda , MICHELS, Martin , WEIGAND, Stefan , ADELT, Isabelle , LAMPE, Thomas
CPC分类号： C07K7/06 , C07K5/0812 , C07K5/1016
摘要： The invention relates to biphenyl-substituted antibacterial macrocycles, to methods for their production, to their use in the treatment and/or prophylaxis of diseases, in addition to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infections.
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公开(公告)号：EP1797110B1
公开(公告)日：2011-01-12
申请号：EP05782906.1
申请日：2005-09-15
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , FREIBERG, Christoph , RADDATZ, Siegfried , MICHELS, Martin , CANCHO-GRANDE, Yolanda , SCHUHMACHER, Joachim , WEIGAND, Stefan
CPC分类号： C07K7/06 , A61K38/00 , C07K5/0812 , C07K5/1016 , Y02A50/475 , Y02A50/481
摘要： The invention relates to antibacterial amide macrocycles and to a method for the production thereof, to the use thereof in the treatment and/or prophylaxis of diseases, and to the use thereof in the production of medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infections.
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公开(公告)号：EP1907413A2
公开(公告)日：2008-04-09
申请号：EP06762521.0
申请日：2006-07-11
CPC分类号： A61K38/12 , C07K5/0202
摘要： The invention relates to antibacterial amide macrocycles and methods for the production thereof, the use thereof for treating and/or preventing diseases, and the use thereof for producing medicaments used for treating and/or preventing diseases, particularly bacterial infections.
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公开(公告)号：EP1515983B1
公开(公告)日：2007-02-21
申请号：EP03738012.8
申请日：2003-06-10
发明人： LAMPE, Thomas , ADELT, Isabelle , BEYER, Dieter , BRUNNER, Nina , ENDERMANN, Rainer , EHLERT, Kerstin , KROLL, Hein-Peter , VON NUSSBAUM, Franz , RADDATZ, Siegfried , RUDOLPH, Joachim , SCHIFFER, Guido , SCHUMACHER, Andreas , CANCHO-GRANDE, Yolanda , MICHELS, Martin , WEIGAND, Stefan
IPC分类号： C07K5/00
CPC分类号： C07D245/04 , A61K38/00 , C07K5/0812
摘要： The invention relates to antibacterial amide macrocycles, to methods for the production thereof, and to the use of the same for producing pharmaceuticals for the treatment and/or prophylaxis of illness, especially bacterial infections.
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公开(公告)号：EP1869068A1
公开(公告)日：2007-12-26
申请号：EP06723614.1
申请日：2006-03-22
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , RADDATZ, Siegfried , MICHELS, Martin , CANCHO-GRANDE, Yolanda , WEIGAND, Stefan , FISCHER, Karin
CPC分类号： C07K5/0812 , C07K5/02 , C07K5/1016 , C07K7/02
摘要： The invention relates to antibacterial amide-macrocycles of formula (I), in which R26 represents hydrogen, halogen, amino or methyl, R7 represents a group of formula (II), (III), (IV) or (V), where R1 represents hydrogen or hydroxy and * stands for the bonding point on the carbon atom, and R2 represents hydrogen or methyl. The invention also relates to a method for producing said macrocycles, to their use for the treatment and/or prophylaxis of diseases and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infections.
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公开(公告)号：EP1797110A1
公开(公告)日：2007-06-20
申请号：EP05782906.1
申请日：2005-09-15
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , FREIBERG, Christoph , RADDATZ, Siegfried , MICHELS, Martin , CANCHO-GRANDE, Yolanda , SCHUHMACHER, Joachim , WEIGAND, Stefan
CPC分类号： C07K7/06 , A61K38/00 , C07K5/0812 , C07K5/1016 , Y02A50/475 , Y02A50/481
摘要： The invention relates to antibacterial amide macrocycles and to a method for the production thereof, to the use thereof in the treatment and/or prophylaxis of diseases, and to the use thereof in the production of medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infections.
摘要翻译： 本发明涉及抗菌酰胺大环化合物及其制备方法，其用于治疗和/或预防疾病的用途，及其在制备用于治疗和/或预防疾病， 特别是细菌感染。
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