发明公开
EP1869174A2 LYASE ENZYMES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
有权
裂解酶酶，NUCLEIC编码使用相同和方法以及
- 专利标题： LYASE ENZYMES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
- 专利标题（中）： 裂解酶酶，NUCLEIC编码使用相同和方法以及
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申请号： EP06748348.7申请日： 2006-03-10
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公开(公告)号： EP1869174A2公开(公告)日： 2007-12-26
- 发明人: WEINER, David , VARVAK, Alexander , RICHARDSON, Toby , PODAR, Mircea , BURKE, Ellen , HEALEY, Shaun
- 申请人： Verenium Corporation
- 申请人地址： 4955 Directors Place San Diego, CA 92121 US
- 专利权人： Verenium Corporation
- 当前专利权人： Verenium Corporation
- 当前专利权人地址： 4955 Directors Place San Diego, CA 92121 US
- 代理机构： Wakerley, Helen Rachael
- 优先权： US660849P 20050310
- 国际公布： WO2006099207 20060921
- 主分类号： C12N9/88
- IPC分类号： C12N9/88
摘要：
This invention provides polypeptides having lyase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides having ammonia lyase activity, e.g., phenylalanine ammonia lyase, tyrosine ammonia lyase and/or histidine ammonia lyase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts. X-NO2, Cl, Br, F, NH2, OH, H, alkyl at one or several o, m, and p positions R-H or alkyl
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