发明授权
- 专利标题: IMPROVED METHODS FOR BEAMING
- 专利标题(中): VERBESSERTE VERFAHRENFÜRBEAMING
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申请号: EP06817236.0申请日: 2006-10-20
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公开(公告)号: EP1948816B1公开(公告)日: 2011-12-07
- 发明人: VOGELSTEIN, Bert , DIEHL, Frank , KINZLER, Kenneth, W. , LI, Ming
- 申请人: The Johns Hopkins University
- 申请人地址: Johns Hopkins Technology Transfer 100 N. Charles Street 5th Floor Baltimore, MD 21201 US
- 专利权人: The Johns Hopkins University
- 当前专利权人: The Johns Hopkins University
- 当前专利权人地址: Johns Hopkins Technology Transfer 100 N. Charles Street 5th Floor Baltimore, MD 21201 US
- 代理机构: Tombling, Adrian George
- 优先权: US729235P 20051024
- 国际公布: WO2007050465 20070503
- 主分类号: C12P19/34
- IPC分类号: C12P19/34
摘要:
Improvements on the basic method used for BEAMing increase sensitivity and increase the signal-to-noise ratio. The improvements have permitted the determination of intrinsic error rates of various DNA polymerases and have permitted the detection of rare and subtle mutations in DNA isolated from plasma of cancer patients.
公开/授权文献
- EP1948816A2 IMPROVED METHODS FOR BEAMING 公开/授权日:2008-07-30
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