发明授权
EP1979351B1 6-PHENYL-1H-IMIDAZO[4, 5-C]PYRIDINE-4-CARBONITRILE DERIVATIVES AS CATHEPSIN K AND S INHIBITORS
有权
6-苯基-1H-咪唑并[4,5-c]吡啶-4-甲腈衍生物作为组织蛋白酶K和-S-缝边
- 专利标题： 6-PHENYL-1H-IMIDAZO[4, 5-C]PYRIDINE-4-CARBONITRILE DERIVATIVES AS CATHEPSIN K AND S INHIBITORS
- 专利标题（中）： 6-苯基-1H-咪唑并[4,5-c]吡啶-4-甲腈衍生物作为组织蛋白酶K和-S-缝边
-
申请号： EP07703872.7申请日： 2007-01-15
-
公开(公告)号： EP1979351B1公开(公告)日： 2010-04-07
- 发明人: CAI, Jiaqiang , RANKOVIC, Zoran , JONES, Philip, Stephen , BENNETT, David, Jonathan , CUMMING, Iain , GILLESPIE, Jonathan
- 申请人： N.V. Organon
- 申请人地址： P.O. Box 20 5349 AB Oss NL
- 专利权人： N.V. Organon
- 当前专利权人： N.V. Organon
- 当前专利权人地址： P.O. Box 20 5349 AB Oss NL
- 代理机构： van Wezenbeek, Petrus M.G.F.
- 优先权： EP06100357 20060116
- 国际公布： WO2007080191 20070719
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/437 ; A61P19/00 ; C07D519/00 ; C07F7/10
摘要：
The present invention relates to 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives having the general Formula (I), to pharmaceutical compositions comprising the same as well as to the use of these derivatives for the preparation of a medicament for the treatment of cathepsin S and/or cathepsin K related diseases such as osteoporosis, atherosclerosis, inflammation and immune disorders, such as rheumatoid arthritis, and chronic pain, such as neuropathic pain.
公开/授权文献
信息查询
