发明公开
EP2001479A2 CO-ADMINISTRATION OF ADENOSINE A1 RECEPTOR ANTAGONISTS AND ANTICONVULSANTS
审中-公开
A1腺苷受体拮抗剂和抗惊厥药的联合管理
- 专利标题： CO-ADMINISTRATION OF ADENOSINE A1 RECEPTOR ANTAGONISTS AND ANTICONVULSANTS
- 专利标题（中）： A1腺苷受体拮抗剂和抗惊厥药的联合管理
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申请号： EP07754928.5申请日： 2007-04-04
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公开(公告)号： EP2001479A2公开(公告)日： 2008-12-17
- 发明人: DITTRICH, Howard , WEBER, Eckard , FARMER, Brian
- 申请人： Novacardia, Inc.
- 申请人地址： One Merck Drive Whitehouse Station, NJ 08889-0100 US
- 专利权人： Novacardia, Inc.
- 当前专利权人： Novacardia, Inc.
- 当前专利权人地址： One Merck Drive Whitehouse Station, NJ 08889-0100 US
- 代理机构： Plougmann & Vingtoft A/S
- 优先权： US789843P 20060406
- 国际公布： WO2007117549 20071018
- 主分类号： A61K31/52
- IPC分类号： A61K31/52 ; A61K31/5513 ; A61K31/635 ; A61P13/02
摘要：
Disclosed herein are pharmaceutical compositions that include an AA1RA, or a salt, ester, amide, metabolite, or prodrug thereof, and an anticonvulsant agent. Also disclosed are methods of treating patients suffering from congestive heart failure, methods of improving renal function, and methods of restoring renal function comprising the step of administering a therapeutically effective amount of an AA1RA or a salt, ester, amide, metabolite, or prodrug thereof, in combination with an anticonvulsant agent.
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