发明公开
EP2029138A1 AMINOTHIAZOLE DERIVATIVES AS HUMAN STEAROYL-COA DESATURASE INHIBITORS
审中-公开
AMINOTHIAZOLDERIVATE ALS人硬脂酰辅酶A DESATURASEHEMMER
- 专利标题： AMINOTHIAZOLE DERIVATIVES AS HUMAN STEAROYL-COA DESATURASE INHIBITORS
- 专利标题（中）： AMINOTHIAZOLDERIVATE ALS人硬脂酰辅酶A DESATURASEHEMMER
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申请号： EP06784578.4申请日： 2006-06-05
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公开(公告)号： EP2029138A1公开(公告)日： 2009-03-04
- 发明人: FU, Jianmin , HOU, Duanjie , KAMBOJ, Rajender , KODUMURU, Vishnumurthy , POKROVSKAIA, Natalia , RAINA, Vandna , SUN, Shaoyi , SVIRIDOV, Serguei , ZHANG, Zaihui
- 申请人： Xenon Pharmaceuticals Inc.
- 申请人地址： 3650 Gilmore Way Burnaby, British Columbia V5G 4W8 CA
- 专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人地址： 3650 Gilmore Way Burnaby, British Columbia V5G 4W8 CA
- 代理机构： Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
- 优先权： US687133P 20060603
- 国际公布： WO2007130075 20071115
- 主分类号： A61K31/426
- IPC分类号： A61K31/426 ; A61K31/427 ; A61K31/4439 ; A61P3/00 ; A61P9/12 ; A61P17/06 ; A61P17/10 ; A61P19/06 ; C07D277/82 ; C07D417/12
摘要：
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I), where V, W, R1, R2, R3 and R4 are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
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