发明公开
- 专利标题： TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY
- 专利标题（中）： 三唑化合物调节HSP90活性
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申请号： EP07795379.2申请日： 2007-05-25
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公开(公告)号： EP2035396A2公开(公告)日： 2009-03-18
- 发明人: YING, Weiwen , PRZEWLOKA, Teresa , CHAE, Junghyun , ZHANG, Shijie , LI, Hao , DU, Zhenjian , JAMES, David , CHIMMANAMADA, Dinesh, U. , NG, Howard, P. , FOLEY, Kevin , DEMKO, Zachary , SUN, Lijun , ZHOU, Dan , QIN, Shuzhen
- 申请人： Synta Pharmaceuticals Corporation
- 申请人地址： 45 Hartwell Avenue Lexington, MA 02421 US
- 专利权人： Synta Pharmaceuticals Corporation
- 当前专利权人： Synta Pharmaceuticals Corporation
- 当前专利权人地址： 45 Hartwell Avenue Lexington, MA 02421 US
- 代理机构： Snodin, Michael D.
- 优先权： US808339P 20060525; US808253P 20060525; US808255P 20060525; US808276P 20060525; US808284P 20060525
- 国际公布： WO2007139967 20071206
- 主分类号： C07D249/12
- IPC分类号： C07D249/12 ; C07D401/04 ; C07D401/14 ; C07D403/04 ; C07D405/04 ; C07D405/14 ; C07D413/14 ; C07D487/04 ; A61K31/4196 ; A61P35/00
摘要：
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
公开/授权文献
- EP2035396B1 TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY 公开/授权日：2014-05-14
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