发明公开
- 专利标题： COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS
- 专利标题（中）： 治疗增殖性疾病的化合物
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申请号： EP07837058.2申请日： 2007-08-20
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公开(公告)号： EP2057117A2公开(公告)日： 2009-05-13
- 发明人: CHEN, Shoujun , KOYA, Keizo , DEMKO, Zachary , SUN, Lijun
- 申请人： Synta Pharmaceuticals Corporation
- 申请人地址： 45 Hartwell Avenue Lexington, MA 02421 US
- 专利权人： Synta Pharmaceuticals Corporation
- 当前专利权人： Synta Pharmaceuticals Corporation
- 当前专利权人地址： 45 Hartwell Avenue Lexington, MA 02421 US
- 代理机构： Snodin, Michael D.
- 优先权： US839034P 20060821; US841408P 20060831
- 国际公布： WO2008024303 20080228
- 主分类号： C07C327/56
- IPC分类号： C07C327/56 ; A61K31/16 ; A61P35/00 ; C07C307/04 ; C07C311/49 ; C07C337/06 ; C07C243/28 ; C07C255/42 ; C07C257/20 ; C07C261/04 ; C07D207/34 ; C07D271/10 ; C07D307/38 ; C07F9/02
摘要：
Disclosed are compounds of formulae (I), (III), (IV), (VII), (X), (XI), (XII), (XIII) and (XIV), wherein the variabables are as defined in the claims, and methods of using compounds of the invention for treating a subject with a proliferative disorder, such as cancer, and methods for treating disorders responsive to Hsp70 induction and/or natural killer induction. Also disclosed are pharmaceutical compositions comprising compounds of the invention and a pharmaceutically acceptable carrier.
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