An ultrasonic therapeutic means and an ultrasonic therapeutic system including the ultrasonic therapeutic means and guided by an imaging device are provided. The ultrasonic therapeutic means includes an ultrasonic therapeutic applicator (5) that comprises an ultrasonic transducer, a box (3) which contains the ultrasonic therapeutic applicator (5) and the couplant liquid, a moving unit (1) which drills through the wall of the box and connects the ultrasonic therapeutic applicator (5), and compensating units (2, 6) which set on the box (3) and holds the level of the liquid when the moving unit (1) drives the ultrasonic therapeutic applicator (5) to move. The compensating units (2, 6) are set on both sides of the box and incorporate with the box, and the moving unit (1) drills through both of the compensating units (2, 6). An ultrasonic therapeutic system including said ultrasonic therapeutic means and guided by an image device is provided. The ultrasonic therapeutic system of the present invention eliminates the phenomena of the level changing of the couplant liquid caused by the moving of the ultrasonic therapeutic applicator driven by the moving unit in the prior art, keeps the stabilization of the liquid level in the box, consequently decreases the interference to imaging results of an imaging device due to the level changing of the couplant liquid, and improves the diagnostic accuracy of the imaging device.