发明公开
EP2061754A1 BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS
审中-公开
联芳和二杂芳基化合物铁代谢紊乱的治疗
- 专利标题： BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS
- 专利标题（中）： 联芳和二杂芳基化合物铁代谢紊乱的治疗
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申请号： EP08744072.3申请日： 2008-03-19
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公开(公告)号： EP2061754A1公开(公告)日： 2009-05-27
- 发明人: CHAFEEV, Mikhail , CHAKKA, Nagasree , CADIEUX, Jean-Jacques , FU, Jianmin , KAMBOJ, Rajender , KODUMURU, Vishnumurthy , LANGILLE, Jonathan , LIU, Shifeng , SUN, Jianyu , SVIRIDOV, Serguei , ZHANG, Zaihui
- 申请人： Xenon Pharmaceuticals Inc.
- 申请人地址： 3650 Gilmore Way Burnaby, British Columbia V5G 4W8 CA
- 专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人地址： 3650 Gilmore Way Burnaby, British Columbia V5G 4W8 CA
- 代理机构： Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
- 优先权： US895662P 20070319
- 国际公布： WO2008115999 20080925
- 主分类号： C07C279/20
- IPC分类号： C07C279/20 ; C07C279/28 ; C07C317/42 ; C07C323/43 ; C07D333/34 ; A61K31/155 ; A61K31/381 ; A61P7/00
摘要：
This invention is directed to compounds of formula (I), wherein A, B, m, n, R1, R2 and R3 are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, for the treatment of iron disorders. This invention is also directed to pharmaceutical compositions comprising the compounds and methods of using the compounds to treat iron disorders.
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