发明授权
- 专利标题： USE OF SPIRO-OXINDOLE COMPOUNDS AS THERAPEUTIC AGENTS
- 专利标题（中）： 使用螺 - 羟吲哚化合物作为疗法
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申请号： EP07868434.7申请日： 2007-10-12
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公开(公告)号： EP2073806B1公开(公告)日： 2012-02-15
- 发明人: CHAFEEV, Mikhail , CHOWDHURY, Sultan , FRASER, Robert , FU, Jianmin , KAMBOJ, Rajender , HOU, Duanjie , LIU, Shifeng , SEID BAGHERZADEH, Mehran , SVIRIDOV, Serguei , SUN, Shaoyi , SUN, Jianyu , CHAKKA, Nagasree , HSIEH, Tom , RAINA, Vandna
- 申请人： Xenon Pharmaceuticals Inc.
- 申请人地址： 3650 Gilmore Way Burnaby, BC V5G 4W8 CA
- 专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人地址： 3650 Gilmore Way Burnaby, BC V5G 4W8 CA
- 代理机构： Grünecker, Kinkeldey, Stockmair & Schwanhäusser
- 优先权： US851787P 20061012
- 国际公布： WO2008060789 20080522
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; A61K31/407 ; A61P3/06 ; A61P13/08 ; A61P17/04 ; A61P35/00
摘要：
This invention is directed to methods of using spiro-oxindole compounds of formula (I): wherein k, j, Q, R1, R2a, R2b, R2c, R2d, R3a, R3b, R3c, and R3d are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, for the treatment and/or prevention of hypercholesterolemia, benign prostatic hyperplasia, pruritis and cancer.
公开/授权文献
- EP2073806A2 USE OF SPIRO-OXINDOLE COMPOUNDS AS THERAPEUTIC AGENTS 公开/授权日：2009-07-01
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