发明授权
EP2094694B1 QUINICLIDINE DERIVATIVES OF (HETERO) ARYLCYCLOHEPTANECARBOXYLIC ACID AS MUSCARINIC RECEPTOR ANTAGONISTS
有权
OF(杂)ARYLCYCLOHEPTANCARBONSÄURENCHINICLIDINDERIVATE作为反对者AM毒蕈碱
- 专利标题: QUINICLIDINE DERIVATIVES OF (HETERO) ARYLCYCLOHEPTANECARBOXYLIC ACID AS MUSCARINIC RECEPTOR ANTAGONISTS
- 专利标题(中): OF(杂)ARYLCYCLOHEPTANCARBONSÄURENCHINICLIDINDERIVATE作为反对者AM毒蕈碱
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申请号: EP07824574.3申请日: 2007-11-13
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公开(公告)号: EP2094694B1公开(公告)日: 2011-01-26
- 发明人: FORD, Rhonan , MATHER, Andrew , METE, Antonio
- 申请人: AstraZeneca AB
- 申请人地址: 151 85 Södertälje SE
- 专利权人: AstraZeneca AB
- 当前专利权人: AstraZeneca AB
- 当前专利权人地址: 151 85 Södertälje SE
- 优先权: US865667P 20061114; US869384P 20061211
- 国际公布: WO2008059245 20080522
- 主分类号: C07D453/02
- IPC分类号: C07D453/02 ; A61K31/439
摘要:
The invention provides compounds of formula (I) wherein R4 is a group of formula (II) or (IIIa) or (IIIb) and R1, R2, R3, R5, a, b and X are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them, a process for preparing pharmaceutical compositions, their use in therapy and intermediates of use in their preparation (I), (II), (IIIa), (IIIb).
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