发明授权
EP2094694B1 QUINICLIDINE DERIVATIVES OF (HETERO) ARYLCYCLOHEPTANECARBOXYLIC ACID AS MUSCARINIC RECEPTOR ANTAGONISTS 有权
OF(杂)ARYLCYCLOHEPTANCARBONSÄURENCHINICLIDINDERIVATE作为反对者AM毒蕈碱

  • 专利标题: QUINICLIDINE DERIVATIVES OF (HETERO) ARYLCYCLOHEPTANECARBOXYLIC ACID AS MUSCARINIC RECEPTOR ANTAGONISTS
  • 专利标题(中): OF(杂)ARYLCYCLOHEPTANCARBONSÄURENCHINICLIDINDERIVATE作为反对者AM毒蕈碱
  • 申请号: EP07824574.3
    申请日: 2007-11-13
  • 公开(公告)号: EP2094694B1
    公开(公告)日: 2011-01-26
  • 发明人: FORD, RhonanMATHER, AndrewMETE, Antonio
  • 申请人: AstraZeneca AB
  • 申请人地址: 151 85 Södertälje SE
  • 专利权人: AstraZeneca AB
  • 当前专利权人: AstraZeneca AB
  • 当前专利权人地址: 151 85 Södertälje SE
  • 优先权: US865667P 20061114; US869384P 20061211
  • 国际公布: WO2008059245 20080522
  • 主分类号: C07D453/02
  • IPC分类号: C07D453/02 A61K31/439
QUINICLIDINE DERIVATIVES OF (HETERO) ARYLCYCLOHEPTANECARBOXYLIC ACID AS MUSCARINIC RECEPTOR ANTAGONISTS
摘要:
The invention provides compounds of formula (I) wherein R4 is a group of formula (II) or (IIIa) or (IIIb) and R1, R2, R3, R5, a, b and X are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them, a process for preparing pharmaceutical compositions, their use in therapy and intermediates of use in their preparation (I), (II), (IIIa), (IIIb).
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