发明公开
- 专利标题： CELL SURFACE DISPLAY, SCREENING AND PRODUCTION OF PROTEINS OF INTEREST
- 专利标题（中）： 细胞表面呈递筛选与目的蛋白质生产
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申请号： EP08727167.2申请日： 2008-03-26
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公开(公告)号： EP2137308A2公开(公告)日： 2009-12-30
- 发明人: RAKESTRAW, James, A. , LIPOVSEK, Dasa
- 申请人： CODON DEVICES, INC
- 申请人地址： One Kendall Square, Building 300, Third Floor Cambridge, MA 02139 US
- 专利权人： CODON DEVICES, INC
- 当前专利权人： CODON DEVICES, INC
- 当前专利权人地址： One Kendall Square, Building 300, Third Floor Cambridge, MA 02139 US
- 代理机构： Trueman, Lucy Petra
- 优先权： US920375P 20070326; US920378P 20070326; US959719P 20070716; US4841 20071201
- 国际公布： WO2008118476 20081002
- 主分类号： C12N15/10
- IPC分类号： C12N15/10 ; C40B40/02
摘要：
Aspects of the invention provide compositions and methods for displaying engineered polypeptides on a cell surface. According to aspects of the invention, immobilized polypeptides can be screened to identify one or more variants having one or more functional or structural properties of interest. Aspects of the invention provide composition and methods for producing engineered protein or protein variants having a functional or a structural property of interest.
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