发明公开
EP2148877A2 INHIBITORS OF HYPOXIA INDUCIBLE FACTOR (HIF) USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS
审中-公开
缺氧诱导因子,用于治疗和过度增生性血管生成相关的疾病抑制剂(HIF)
- 专利标题: INHIBITORS OF HYPOXIA INDUCIBLE FACTOR (HIF) USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS
- 专利标题(中): 缺氧诱导因子,用于治疗和过度增生性血管生成相关的疾病抑制剂(HIF)
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申请号: EP08758408.2申请日: 2008-05-08
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公开(公告)号: EP2148877A2公开(公告)日: 2010-02-03
- 发明人: BOYER, Stephen , HÄRTER, Michael , WICKENS, Philip , PATEL, Manoj , KUMARASINGHE, Ellalahewage, Sathyajith , BHARGAVA, Ajay, Kumar , THIERAUCH, Karl-Heinz , BECK, Hartmut , GRESCHAT, Susanne , ELLINGHAUS, Peter , PAULUS, Patrick , HESS-STUMPP, Holger
- 申请人: Bayer Schering Pharma Aktiengesellschaft
- 申请人地址: Müllerstrasse 178 13353 Berlin DE
- 专利权人: Bayer Schering Pharma Aktiengesellschaft
- 当前专利权人: Bayer Schering Pharma Aktiengesellschaft
- 当前专利权人地址: Müllerstrasse 178 13353 Berlin DE
- 优先权: US930816P 20070518
- 国际公布: WO2008141731 20081127
- 主分类号: C07D403/04
- IPC分类号: C07D403/04 ; C07D413/04 ; C07D413/14 ; C07D471/04 ; C07D491/04 ; A61K31/4245 ; A61P35/00
摘要:
This invention relates to novel heteroaryl substituted pyrazole compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients or therapeutic measures.
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