发明公开
- 专利标题： NOVEL DICARBOXYLIC ACID DERIVATIVES AS S1P1 RECEPTOR AGONISTS
- 专利标题（中）： 新二AS S1P1受体拮抗剂
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申请号： EP08761078.8申请日： 2008-06-16
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公开(公告)号： EP2170850A1公开(公告)日： 2010-04-07
- 发明人: CAPET, Marc , LEVOIN, Nicolas , BERREBI-BERTRAND, Isabelle , ROBERT, Philippe , SCHWARTZ, Jean-Charles , LECOMTE, Jeanne-Marie , ARADHYE, Jayraj Dilipbhai , PILLAI, Muthukumaran Natarajan , PANCHAL, Bhavesh Mohanbhai , JIVANI, Jignesh Kantilal , SAMANTA, Biswajit , PAL, Ranjan Kumar , THENNATI, Rajamannar
- 申请人： BIOPROJET , Sun Pharma Advanced Research Company Ltd
- 申请人地址： 30, rue des Francs-Bourgeois 75003 Paris FR
- 专利权人： BIOPROJET,Sun Pharma Advanced Research Company Ltd
- 当前专利权人： BIOPROJET,Sun Pharma Advanced Research Company Ltd
- 当前专利权人地址： 30, rue des Francs-Bourgeois 75003 Paris FR
- 代理机构： Jacobson, Claude
- 优先权： EP07290748 20070615
- 国际公布： WO2008152149 20081218
- 主分类号： C07D271/06
- IPC分类号： C07D271/06 ; C07D413/10 ; C07D413/14 ; A61K31/4245 ; A61P29/00 ; A61P37/06
摘要：
The present invention relates to new compounds of formula (I) possessing agonistic activity at sphingosine-1 -phosphate (S1 P) receptors, their process of preparation and their use as immunosuppressive agents. The invention is also directed to pharmaceutical compositions containing these compounds and use of these compounds for treatment/prevention of immune mediated diseases and conditions or inflammatory diseases and conditions.
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