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公开(公告)号：EP2697219A1
公开(公告)日：2014-02-19
申请号：EP12714674.4
申请日：2012-04-10
发明人： CAPET, Marc , BERREBI-BERTRAND, Isabelle , ROBERT, Philippe , SCHWARTZ, Jean-Charles , LECOMTE, Jeanne-Marie , THENNATI, Rajamannar , PAL, Ranjan, Kumar , SAMANTA, Biswajit , PILLAI, Muthukumaran, Natarajan , DESAI, Japan, Nitinkumar , RANA, Dijixa, Chandubhai , PRAJAPATI, Kaushik, Dhanjubhai , PATHAK, Sandeep, Pankajbhai , PANCHAL, Bhavesh, M. , ARADHYE, Jayraj, D.
IPC分类号： C07D413/10 , A61K31/454 , A61P9/10 , A61P29/00 , A61P37/06 , A61P35/00 , C07D413/14 , A61K31/5377
CPC分类号： C07D413/10 , A61K31/454 , A61K45/06 , C07D271/06
摘要： The present invention relates to novel compounds acting as agonists at S1P (sphingosine-1-phosphate) receptors, compositions containing these compounds, use of these compounds in medicine and their process of preparation.
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公开(公告)号：EP2697219B1
公开(公告)日：2015-03-04
申请号：EP12714674.4
申请日：2012-04-10
发明人： CAPET, Marc , BERREBI-BERTRAND, Isabelle , ROBERT, Philippe , SCHWARTZ, Jean-Charles , LECOMTE, Jeanne-Marie , THENNATI, Rajamannar , PAL, Ranjan, Kumar , SAMANTA, Biswajit , PILLAI, Muthukumaran, Natarajan , DESAI, Japan, Nitinkumar , RANA, Dijixa, Chandubhai , PRAJAPATI, Kaushik, Dhanjubhai , PATHAK, Sandeep, Pankajbhai , PANCHAL, Bhavesh, M. , ARADHYE, Jayraj, D.
IPC分类号： C07D413/10 , A61K31/454 , A61P9/10 , A61P29/00 , A61P37/06 , A61P35/00 , C07D413/14 , A61K31/5377
CPC分类号： C07D413/10 , A61K31/454 , A61K45/06 , C07D271/06
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公开(公告)号：EP2170850B1
公开(公告)日：2014-09-24
申请号：EP08761078.8
申请日：2008-06-16
发明人： CAPET, Marc , LEVOIN, Nicolas , BERREBI-BERTRAND, Isabelle , ROBERT, Philippe , SCHWARTZ, Jean-Charles , LECOMTE, Jeanne-Marie , ARADHYE, Jayraj Dilipbhai , PILLAI, Muthukumaran Natarajan , PANCHAL, Bhavesh Mohanbhai , JIVANI, Jignesh Kantilal , SAMANTA, Biswajit c/o SUN PHARMA ADVANCED RESEARCH CENTRE , PAL, Ranjan Kumar c/o SUN PHARMA ADVANCED RESEARCH CENTRE , THENNATI, Rajamannar c/o SUN PHARMA ADVANCED RESEARCH CENTRE
IPC分类号： C07D271/06 , C07D413/10 , C07D413/14 , A61K31/4245 , A61P29/00 , A61P37/06
CPC分类号： C07D413/10 , C07D271/06 , C07D413/14
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公开(公告)号：EP2170850A1
公开(公告)日：2010-04-07
申请号：EP08761078.8
申请日：2008-06-16
发明人： CAPET, Marc , LEVOIN, Nicolas , BERREBI-BERTRAND, Isabelle , ROBERT, Philippe , SCHWARTZ, Jean-Charles , LECOMTE, Jeanne-Marie , ARADHYE, Jayraj Dilipbhai , PILLAI, Muthukumaran Natarajan , PANCHAL, Bhavesh Mohanbhai , JIVANI, Jignesh Kantilal , SAMANTA, Biswajit , PAL, Ranjan Kumar , THENNATI, Rajamannar
IPC分类号： C07D271/06 , C07D413/10 , C07D413/14 , A61K31/4245 , A61P29/00 , A61P37/06
CPC分类号： C07D413/10 , C07D271/06 , C07D413/14
摘要： The present invention relates to new compounds of formula (I) possessing agonistic activity at sphingosine-1 -phosphate (S1 P) receptors, their process of preparation and their use as immunosuppressive agents. The invention is also directed to pharmaceutical compositions containing these compounds and use of these compounds for treatment/prevention of immune mediated diseases and conditions or inflammatory diseases and conditions.
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5.发明授权DERIVATIVES OF 1-N-AZACYCLOALKYL-3-PHENOXYPROPANE USEFUL FOR THE PREPARATION OF PSYCHOTROPIC MEDICAMENTS 有权用于生产精神药品的1-N-氮杂环烷基-3-苯氧合适的衍生物
公开(公告)号：EP1874746B1
公开(公告)日：2015-11-18
申请号：EP06744550.2
申请日：2006-04-25
申请人： BIOPROJET
发明人： BERTRAND, Isabelle , CAPET, Marc , LECOMTE, Jeanne-Marie , LEVOIN, Nicolas , LIGNEAU, Xavier , POUPARDIN-OLIVIER, Olivia , ROBERT, Philippe , SCHWARTZ, Jean-Charles , LABEEUW, Olivier
IPC分类号： C07D295/088 , C07D213/30 , C07D211/68 , C07D333/16 , C07D211/14 , C07D401/10 , A61K31/40 , A61K31/44 , A61K31/381 , A61K31/5377
CPC分类号： C07D213/30 , C07D207/20 , C07D207/30 , C07D207/335 , C07D211/22 , C07D211/42 , C07D211/46 , C07D211/68 , C07D211/70 , C07D213/61 , C07D213/64 , C07D213/89 , C07D231/12 , C07D295/088 , C07D295/192 , C07D333/16 , C07D333/20 , C07D401/12 , C07D401/14 , C07D409/12 , C07D413/12
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6.发明公开A COMBINATION OF ADRENALIN WITH AN ANTIDEPRESSANT FOR USE IN THE TREATMENT OF SHOCKS 有权肾上腺素与用于过敏性休克的治疗中使用的抗抑郁药组合
公开(公告)号：EP2903607A1
公开(公告)日：2015-08-12
申请号：EP13771500.9
申请日：2013-10-02
申请人： Bioprojet
发明人： SCHWARTZ, Jean-Charles , LIGNEAU, Xavier , LANDAIS, Laurent, François, Gérard , PERRIN, David , LECOMTE, Jeanne-Marie
IPC分类号： A61K31/165 , A61K31/335 , A61K31/55 , A61K45/06 , A61P37/08
CPC分类号： A61K31/335 , A61K9/0019 , A61K31/137 , A61K45/06 , A61K2300/00
摘要： The present invention concerns a novel combination of adrenalin with an antidepressant and its use as a pharmaceutical composition for the treatment of shocks. The pharmaceutical composition is to be administered by injection.
摘要翻译： 本发明涉及具有抗抑郁和其作为冲击的治疗的药物组合物中使用的新颖的肾上腺素组合。 所述药物组合物通过注射给药。
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公开(公告)号：EP1874747A1
公开(公告)日：2008-01-09
申请号：EP06744570.0
申请日：2006-04-26
申请人： BIOPROJET
发明人： BERTRAND, Isabelle , CAPET, Marc , LECOMTE, Jeanne-Marie , LEVOIN, Nicolas , LIGNEAU, Xavier , POUPARDIN-OLIVIER, Olivia , ROBERT, Philippe , SCHWARTZ, Jean-Charles
IPC分类号： C07D295/088 , C07D307/79 , C07D317/54 , C07D319/18 , A61K31/40 , A61K31/445 , A61P25/00
CPC分类号： C07D295/088 , C07D307/79 , C07D317/54 , C07D319/18
摘要： The present patent application concerns new compounds of formula (I) with R1 and R2 taken together with the nitrogen atom to which they are attached, form a saturated nitrogen-containing ring, A is a saturated C1 -4 alkylene and B a C3-4 alkylene or alkenylene chain; their preparation and their use as a H3 receptor ligand for treating e.g. CNS disorders like Alzheimer's disease.
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8.发明公开
公开(公告)号：EP1863487A2
公开(公告)日：2007-12-12
申请号：EP06744466.1
申请日：2006-03-30
申请人： BIOPROJET
IPC分类号： A61K31/4453 , A61P25/16 , A61P25/28
CPC分类号： A61K31/4453
摘要： The present invention provides new method of treatment of Parkinson's disease, obstructive sleep apnea, narcolepsy, dementia with Lewy bodies, vascular dementia with non-imidazole alkylamine derivatives that constitute antagonists of the H3-receptors of histamine.
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9.发明公开NEW COMBINATIONS OF AN ANTI EMETIC AGENT AND AN ENKEPHALINASE INHIBITOR 有权有5-HT3受体拮抗剂或消旋卡多曲的新组合DEXECADOTRIL
公开(公告)号：EP1718337A1
公开(公告)日：2006-11-08
申请号：EP05702484.6
申请日：2005-02-14
申请人： BIOPROJET
IPC分类号： A61K45/06 , A61K31/4178 , A61K31/439 , A61K31/265 , A61P1/12
CPC分类号： A61K45/06 , A61K31/265 , A61K31/4178 , A61K31/439 , A61K2300/00
摘要： The present invention concerns new combinations of an anti-emetic agent and an enkephalinase inhibitor, the uses of said combinations for treating diarrhea and/or gastroenteritis.
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公开(公告)号：EP0828851B1
公开(公告)日：2005-07-20
申请号：EP96916181.9
申请日：1996-05-09
发明人： ROSE, Christiane , VARGAS, Froylan , BOURGEAT, Pierre , SCHWARTZ, Jean-Charles , BISHOP, Paul, Beaumont , BAMBAL, Ramesh, Babarao , GANELLIN, Charon, Robin , LEBLOND, Bertrand , MOORE, Andrew, N., J. , CHAN, Suzanne , LIHUA, Zhao
CPC分类号： C07K5/06052 , A61K38/00 , C07D209/42 , C07K5/06026 , C07K5/06191 , C12Q1/37 , G01N2333/595
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