发明公开
EP2187950A1 USE OF INSULIN C-PEPTIDE, ALONE OR IN COMBINATION WITH GLP-1, AS A THERAPEUTIC AGENT
审中-公开
胰岛素USE C-肽，单独或与GLP-1组合的治疗剂
- 专利标题： USE OF INSULIN C-PEPTIDE, ALONE OR IN COMBINATION WITH GLP-1, AS A THERAPEUTIC AGENT
- 专利标题（中）： 胰岛素USE C-肽，单独或与GLP-1组合的治疗剂
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申请号： EP08802009.4申请日： 2008-09-09
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公开(公告)号： EP2187950A1公开(公告)日： 2010-05-26
- 发明人: BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
- 申请人： Mondobiotech Laboratories AG
- 申请人地址： Herrengasse 21 9490 Vaduz LI
- 专利权人： Mondobiotech Laboratories AG
- 当前专利权人： Mondobiotech Laboratories AG
- 当前专利权人地址： Herrengasse 21 9490 Vaduz LI
- 代理机构： Arth, Hans-Lothar
- 优先权： EP07017765 20070911
- 国际公布： WO2009039963 20090402
- 主分类号： A61K38/28
- IPC分类号： A61K38/28 ; A61K38/26 ; A61P31/00 ; A61P35/00 ; A61P37/00 ; A61P3/00 ; A61P9/00 ; A61P11/00 ; A61P25/28 ; A61P31/20 ; A61P31/18 ; A61P31/06 ; A61P31/04
摘要：
The present invention is directed to the use of the peptide compound Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-GIn-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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